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Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analyticaland life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems.From the contents:* Theory and practice of SERS* Analytical applications* SERS combined with other analytical techniques* Biophysical applications* Life science applications including various microscopiesAimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.
List of contents
PrefaceBASIC ELECTROMAGNETIC THEORY OF SERSIntroductionPlasmon Resonances and Field EnhancementsField Enhancement Distribution and LocalizationElectromagnetic Model for the SERS and Fluorescence Enhancement FactorsThe Magnitude of the SERS Enhancement Factor in Typical CasesConclusionsNANOPARTICLE SERS SUBSTRATESIntroductionPreparation and Stability of Metal Nanoparticle Colloidal SERS SubstratesCharacterization of Nanoparticle-Based SERS SubstratesNanoparticles on the Unfunctionalized Solid Surface as SERS SubstratesConclusion and OutlookQUANTITATIVE SERS METHODSIntroductionSERS MediaStability and Shelf LifeReproducibility and Internal StandardsSelectivityConclusionSINGLE-MOLECULE- AND TRACE DETECTION BY SERSIntroductionExperiments and ResultsConclusionsDETECTION OF PERSISTENT ORGANIC POLLUTANTS BY USING SERS SENSORS BASED ON ORGANICALLY FUNCTIONALIZED Ag NANOPARTICLESIntroductionInclusion HostsContact HostsOcclusion HostsConclusionsSERS AND PHARMACEUTICALSIntroductionSERS of Antipyretics and AnalgesicsSERS of AntimalarialsSERS of Anticarcinogenics andf AntimutagenicsConcluding RemarksSERS AND SEPARATION SCIENCEIntroductionSERS and Capillary Electrophoresis (CE)SERS and Liquid Chromatography (LC)SERS and Gas Chromatography (GC)SERS and Thin Layer Chromatography (TLC)Other Separation MethodsConclusionsSERS AND MICROFLUIDICSIntroductionLab-on-a-Chip TechnologyMicrofluidic Platforms and Application for SERSSummaryELECTROCHEMICAL SERS AND ITS APPLICATION IN ANALYTICAL, BIOPHYSICAL AND LIFE SCIENCEElectrochemical Surface-Enhanced Raman SpectroscopyFeatures of Electrochemical Surface-Enhanced Raman SpectroscopyExperimental Techniques of EC-SERSApplications of EC-SERSPerspectivesELECTRON TRANSFER OF PROTEINS AT MEMBRANE MODELSIntroductionModel Membranes and Membrane ModelsMethods for Probing Electron Transfer Processes of Cytochrome c at Coated ElectrodesThe Unusual Distance Dependence of the Interfacial Electron Transfer ProcessElectron Transfer and Protein Orientational DynamicsElectric Field Effects on the Electron Transfer DynamicsElectron Transfer and Protein Structural ChangesOverall Description of the Mechanism and Dynamics of the Interfacial ProcessesInterfacial Electric Fields and the Biological Functions of Cytochrome cQUANTITATIVE DNA ANALYSIS USING SURFACE-ENHANCED RESONANCE RAMAN SCATTERINGIntroductionSERRS SurfacesRaman ReportersSERRS DNA ProbesSensitivityMultiplexingAssaysConclusionSERS MICROSCOPY: NANOPARTICLE PROBES AND BIOMEDICAL APPLICATIONSIntroductionSERS Nanoparticle ProbesBiomedical Applications of SERS MicroscopySummary and Outlook1-P AND 2-P EXCITED SERS AS INTRACELLULAR PROBEFrom Tags to Probes: Challenges in Intracellular ProbingProbing of Intracellular ParametersSurface-Enhanced Hyper Raman Scattering and Its Potential in Studies of CellsSURFACE- AND TIP-ENHANCEMENT CARSIntroductionCARS: Coherent Anti-Stokes Raman ScatteringLocal Enhancement of CARS by Metallic NanostructuresSurface-Enhanced CARSTip-Enhanced CARS
About the author
Sebastian Schlücker obtained his undergraduate and PhD degrees at the University of Würzburg, Germany. After a postdoctoral stay at the US National Insitute of Health (NIH), Bethesda, Maryland, USA from 2002 till 2004, he completed his habilitation in 2006 at the University of Würzburg. He has been Professor of Experimental Physics at the Universtiy of Osnabrück, Germany since 2008.
Summary
Covering everything from the basic theoretical and practical knowledge to new exciting developments in the field with a focus on analytical
and life science applications, this monograph shows how to apply surface-enhanced Raman scattering (SERS) for solving real world problems.
From the contents:
* Theory and practice of SERS
* Analytical applications
* SERS combined with other analytical techniques
* Biophysical applications
* Life science applications including various microscopies
Aimed at analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists. Includes a Foreword by the renowned Raman spectroscopist Professor Wolfgang Kiefer, the former Editor-in-Chief of the Journal of Raman Spectroscopy.
Report
"The book Surface Enhanced Raman Spectroscopy: Analytical, Biophysical and Life Science Applications provides a well-balanced account of the basic principles of SERS, advances in the SERS method, and applications of SERS technology. The book is expected to become a valuable resource for researchers in the field of SERS and those from other fields who are interested in exploiting SERS technology in a growing number of analytical, biophysical and life science applications." ( Anal Bioanal Chem , 2011)
"I highly recommend it to any researcher in materials science and spectroscopy as well as any researchers in surface and medicinal chemistry and biophysics with some background in molecular spectroscopy. The 14 chapters masterfully guide the reader through a fascinating field in which researchers have been very active over the last decade." (Optics & Photonics News, 5 August 2011)
