DNA Repair and Human Disease

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

List of contents

Human Premature Aging Disorders and Dysfunction of DNA Repair.- DNA Repair Aspects for RecQ Helicase Disorders.- Trichothiodystrophy.- Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair.- Radiosensitivity of Cells Derived from Down Syndrome Patients.- The Fanconi Anemia/BRCA Pathway.- Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators?.- Mechanisms of DNA Damage and Repair in Alzheimer Disease.- Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells.- Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients.

Summary

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

Product details

• Authors: Adayabalam Balajee
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 01.01.2014
• EAN: 9781489998996
• ISBN: 978-1-4899-9899-6
• No. of pages: 150
• Dimensions: 155 mm x 9 mm x 235 mm
• Weight: 260 g
• Illustrations: XII, 150 p.
• Series: Medical Intelligence Unit; Medical Intelligence Unit
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; B, Medical microbiology & virology, Human Genetics, Biomedical and Life Sciences, Medical Genetics, Cellular biology (cytology), Medical Microbiology, Cell Biology