Fr. 220.00

Jnk Signaling Pathway

English · Hardback

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Informationen zum Autor Anning Lin Ph.D. is an Associate Professor at Ben M ay Institute for Cancer Research and the Program Leader of the Cell Signaling and Gene Regulation Program of Cancer Research Center, University of Chicago, U.S.A. His main research interests include the function of the intracellular signaling network in programmed cell death and tumorigenesis, using the c-Jun N-terminal protein kinase (JNK) and IkB kinase (IKK) signaling pathways as molecular probes. Klappentext Signal transduction is one of the most exciting research areas in modern biology as it deals with how information flows from the extracellular environment into a living cell to change its metabolism, genotype and phenotype Zusammenfassung Signal transduction is one of the most exciting research areas in modern biology as it deals with how information flows from the extracellular environment into a living cell to change its metabolism, genotype and phenotype Inhaltsverzeichnis Preface 1. The Discovery of JNK and Its Biological Functions 2. Regulation of JNK by Small GTPases 3. Physiological Roles of the Different JNKs: Lessons from the JNK Knockouts 4. The Biological Function of JNKKs (MKK4/MKK7 Knockout Mice) 5. The JNK Signal Transduction Pathway in Drosophila 6. Regulation of Apoptosis by the JNK Signaling Pathway 7. Oxidative Stress, JNK Activation and Cell Death 8. JNK as a Therapeutic Target

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