Functional Coherence of Molecular Networks in Bioinformatics

Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks is commonly used for systems level analysis of biological function; research and method development in this area has grown tremendously in the past few years. This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective.

List of contents

Introduction to Network Biology.- Topological Characteristics of Molecular Networks.- Functional Annotation in Gene Networks.- Proteome Network Emulating Models.- Biological Network Alignment.- Pattern Mining across many Massive Biological Networks.- Molecular Networks and Complex Diseases.- Moving Towards Genome-Scale Kinetic Models: The Mass Action Stoichiometric Simulation Approach.- Index.

Summary

Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks is commonly used for systems level analysis of biological function; research and method development in this area has grown tremendously in the past few years. This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective.

Product details

• Assisted by: Ananth Grama (Editor), Mehmet Koyuturk (Editor), Mehmet Koyutürk (Editor), Shanka Subramaniam (Editor), Shankar Subramaniam (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 01.01.2014
• EAN: 9781489996404
• ISBN: 978-1-4899-9640-4
• No. of pages: 228
• Dimensions: 158 mm x 237 mm x 13 mm
• Weight: 373 g
• Illustrations: X, 228 p.
• Subjects: Natural sciences, medicine, IT, technology > Biology > Miscellaneous; B, computer science, bioinformatics, Computer Science, general, Life sciences: general issues, Biomedical and Life Sciences, Systems Biology, Information technology: general issues, Biomedical Engineering and Bioengineering, Biomedical engineering, Computational and Systems Biology, Computational Biology/Bioinformatics