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This book would combine chapters written by the most qualified authors around the world whose research encompasses the effect of morphine or other opioids on tumor growth and metastasis. This includes clinicians involved in trials determining which type of post surgical pain management can minimize the risk of recurrence or metastasis, researchers working on animal models and studying the effect of morphine on tumors, and most importantly the mechanism for this effect, and lastly cell biologists. There is currently a lot of research going on trying to reconcile the pro- and anti-cancer aspects of opioids actions.
List of contents
1 Morphine and metastasis: from bench to bedside.- 2 Interaction of Naloxone and Estrogen Receptor in Breast Cancer.- 3 Morphine and immunosuppression in the context of tumor growth and metastasis.- 4 Opioid Regulation of Vascular Integrity.- 5 Iatrogenic Angiogenesis.- 6 Could opioids affect cancer recurrence or metastases? Current experimental and Translational Evidence.- 7 Genetic polymorphisms in the µ-opioid receptor gene and breast cancer survival.- 8 Anaesthetic and pain management technique in long term cancer outcome - benefits of regional anaesthesia and analgesia in the context of cancer surgery.- 9 Perioperative morphine and cancer recurrence.
Summary
This book would combine chapters written by the most qualified authors around the world whose research encompasses the effect of morphine or other opioids on tumor growth and metastasis. This includes clinicians involved in trials determining which type of post surgical pain management can minimize the risk of recurrence or metastasis, researchers working on animal models and studying the effect of morphine on tumors, and most importantly the mechanism for this effect, and lastly cell biologists. There is currently a lot of research going on trying to reconcile the pro- and anti-cancer aspects of opioids actions.
