Deciphering Growth

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism's body size, which is not only limited to the size of the brain.

List of contents

Evolutionary Trends in Body Size.- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation.- Genetic Control of Size at Birth.- The GH/IGF-1 Axis: Insights from Animal Models.- Downstream Mechanisms of Growth Hormone Action.- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I.- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action.- IGF-I Deficiency: Lessons from Human Mutations.- Putting IGF-I Biology into a Clinical Perspective.- IGF Resistance: The Role of the Type 1 IGF Receptor.- The Importance of the National Cooperative Growth Study (NCGS).- Why we are Treating Children with Growth Hormone: Lessons from the French Registry.

Summary

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism’s body size, which is not only limited to the size of the brain.

Product details

• Assisted by: A Kelly (Editor), A Kelly (Editor), -C Carel (Editor), J -C Carel (Editor), J. -C. Carel (Editor), J.-C. Carel (Editor), Paul A. Kelly (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 01.01.2014
• EAN: 9783642421297
• ISBN: 978-3-642-42129-7
• No. of pages: 155
• Dimensions: 155 mm x 9 mm x 235 mm
• Weight: 272 g
• Illustrations: XIII, 155 p.
• Series: Research and Perspectives in Endocrine Interactions; Research and Perspectives in Endocrine Interactions
• Subjects: Natural sciences, medicine, IT, technology > Biology; C, HUMAN PHYSIOLOGY, Biomedical and Life Sciences, tissue, growth hormone