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Practical Nuclear Medicine Physics provides a readable explanation of the physics behind radiobiology, radiation detection, and molecular imaging with gamma and PET cameras. Case-based scenarios illustrate common artifacts and pitfalls, and a concluding chapter provides 20 annotated questions and answers.
List of contents
- Introduction to Nuclear Medicine
- Radiation
- X-rays
- Nuclear nomenclature
- Nuclear radiation
- Electron capture
- Beta emission
- Positron emission
- Alpha emission
- Isomeric transition
- Gamma radiation
- Internal conversion
- Auger electrons
- Units of radioactivity
- Radiobiology
- Units of radiation exposure
- Deterministic effects
- Stochastic effects
- Radiation safety
- Radiation detectors - ionization detectors
- Ionization chambers
- Dose calibrators
- Survey meters
- Proportional counters
- Radiation detectors - single photon
- Collimators
- Scintillators
- Photomultiplier tubes
- The gamma camera
- Static planar imaging
- Dynamic imaging
- Gated imaging
- SPECT
- SPECT/CT
- Gamma probes and well counters
- Radiation detection - PET
- PET principles
- PET acquisition and reconstruction
- Time of flight
- PET/CT
- PET/MR
- Dose calibrator artifacts
- Case 1. Altitude
- Case 2. Geometry
- Case 3. Materials
- Gamma camera artifacts
- Case 1. Cracked crystal
- Case 2. Hygroscopic crystal
- Case 3. PMT malfunction
- Case 4. Flood nonuniformity
- Planar acquisition artifacts
- Case 1. Off peak acquisition
- Case 2. Motion artifact
- Case 3. Dose infiltration
- Case 4. Collimator penetration
- SPECT acquisition artifacts
- Case 1. Center of rotation error
- Case 2. Filtered back projection streak
- Case 3. Noisy images
- Case 4. Iterative reconstruction errors
- Case 5. Motion artifact
- PET acquisition artifacts
- Case 1. PMT malfunction
- Case 2. Crystal temperature instability
- Case 3. Table misregistration
- Case 4. Scatter correction errors
- Case 5. Attenuation correction errors
- Case 6. CT artifacts affecting PET reconstruction
- Dose calibrator pitfalls
- Case 1. Dose calibrator contamination
- Case 2. Wrong setting used on dose calibrator
- Case 3. High background activity
- Single photon pitfalls
- Case 1. Prostheses
- Case 2. Recent prior study
- Case 3. Contamination
- Case 4. Poor dynamic timing
- Case 5. Background activity
- PET pitfalls
- Case 1. Infiltration
- Case 2. Treatment effect mimics new disease
- Case 3. Misregistration and attenuation correction
- Case 4. Respiratory motion artifact
- Therapy pitfalls
- Case 1. Empiric dosing exceeds safe limits
- Case 2. GI toxicity
- Case 3. Radioactive vomit
- Case 4. Therapy infusion via indwelling catheter
- Puzzlers
About the author
Assistant Professor of Radiology; Clinical Director of Nuclear Medicine/Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
Summary
Practical Nuclear Medicine Physics provides a readable explanation of the physics behind radiobiology, radiation detection, and molecular imaging with gamma and PET cameras. Case-based scenarios illustrate common artifacts and pitfalls, and a concluding chapter provides 20 annotated questions and answers.
Additional text
I am delighted to recommend it to people starting out in nuclear medicine and certainly I think it will be helpful to have it on the shelf in the department.
