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Informationen zum Autor Vijay Kumar Thakur , PhD, is a Staff Scientist in the School of Mechanical and Materials Engineering at Washington State University, U.S.A. He has published more than 100 research articles, patents and conference proceedings in the field of polymers and materials science and has published ten books and 25 book chapters on the advanced state-of-the-art of polymers/ materials science. He has extensive expertise in the synthesis of polymers (natural/ synthetic), nano materials, nanocomposites, biocomposites, graft copolymers, high performance capacitors and electrochromic materials. Manju Kumari Thakur works in the Department of Chemistry, Himachal Pradesh University, Simla, India. Klappentext Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications. Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers Inhaltsverzeichnis Preface xvii 1 Particle Engineering of Polymers into Multifunctional Interactive Excipients 1 Sharad Mangal, Ian Larson, Felix Meiser and David AV Morton 1.1 Introduction 1 1.2 Polymers as Excipients 3 1.3 Material Properties Affecting Binder Activity 6 1.3.1 Particle Size 6 1.3.2 Deformation Mechanisms 7 1.3.3 Glass Transition Temperature (Tg) 8 1.4 Strategies for Improving Polymeric Filler-Binder Performance for Direct Compression 8 1.4.1 Interactive Mixing 12 1.4.2 Challenges to Interactive Mixing 13 1.4.3 Controlling Interparticle Cohesion 14 1.5 Preparation and Characterization of Interactive Excipients 14 1.5.1 Particle Size and Size Distribution of Excipients 15 1.5.2 Effect of L-leucine on Surface Morphology 16 1.5.3 Effect of L-leucine on Surface Composition 16 1.5.4 Effect of L-leucine on Surface Energy 17 1.5.5 Effect of L-leucine on Interparticle Cohesion 18 1.6 Performance of Interactive Excipients 18 1.6.1 Blending Ability 18 1.6.2 Effect on Flow 20 1.6.3 Binder Activity 20 1.7 Investigation of the Effect of Polymer Mechanical Properties 23 1.8 Conclusion 25 References 26 2 The Art of Making Polymeric Membranes 33 K.C. Khulbe, T. Matsuura and C. Feng 2.1 Introduction 33 2.2 Types of Membranes 35 2.2.1 Porous Membranes 35 2.2.2 Nonporous Membranes 36 2.2.3 Liquid Membranes (Carrier Mediated Transport) 36 2.2.4 Asymmetric Membranes 36 2.3 Preparation of Membranes 36 2.3.1 Phase Inversion/Separation 37 2.3.2 Vapor-Induced Phase Separation (VIPS) 37 2.3.3 Thermally-Induced Phase Separation (TIPS) 37 2.3.4 Immersion Precipitation 38 2.3.5 Film/Dry Casting Technique 38 2.3.6 Track Etching 39 ...
