Read more
The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality. Edited by the Nobel laureate R. H. Grubbs and A. G. Wenzel, this volume 1 of the 3-volume work focusses on catalyst development and mechanism. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry.Other available volumes:Volume 2: Applications in Organic Synthesis, Editors: R. H. Grubbs and D. J. O´LearyVolume 3: Polymer Synthesis, Editors: R. H. Grubbs and E. Khosravi
List of contents
PrefaceHIGH-OXIDATION ON STATE MOLYBDENUM AND TUNGSTEN COMPLEXES RELEVANT TO OLEFIN METATHESISIntroductionNew Imido Ligands and Synthetic ApproachesBispyrrolide and Related ComplexesMonoalkoxide Pyrrolide (MAP) ComplexesReactions of Alkylidenes with OlefinsOlefin and Metallacyclopentane ComplexesTungsten Oxo ComplexesBisaryloxidesOther ConstructsConclusionsALKANE METATHESISIntroductionAlkane Metathesis by Single-Catalyst SystemsAlkane Metathesis by Tandem, Dual-Catalytic SystemsConclusionDIASTEREOCONTROL IN OLEFIN METATHESIS: THE DEVELOPMENT OF Z-SELECTIVE RUTHENIUM CATAYLSTSIntroductionThe Challenge of Z-Selective Olefin MetathesisPrevious StrategiesA Serendipitous DiscoveryCatalyst StudiesApplications of Z-Selective Ru Metathesis CatalystsConclusionRUTHENIUM OLEFIN METATHESIS CATALYSTS SUPPORTED BY CYCLIC ALKYL AMINOCARBENES (CAACs)IntroductionProperties and Preparation of CAAC LigandsCAAC-Supported, Ruthenium Olefin Metathesis CatalystsSummarySUPPORTED CATALYSTS AND NONTRADITIONAL REACTION MEDIAIntroductionSupported Catalyst SystemsOlefin Metathesis in Nontraditional MediaConclusionsINSIGHTS FROM COMPUTATIONAL STUDIES ON d0 METAL-CATALYZED ALKENE AND ALKYNE METATHESIS AND RELATED REACTIONSIntroductionAlkene MetathesisAlkyne MetathesisAlkane MetathesisOutlookCOMPUTATIONAL STUDIES OF RUTHENIUM-CATALYZED OLEFIN METATHESISIntroductionComputational Investigations of Non-Chelated Ruthenium CatalystsComputational Investigations of Chelated, Z-Selective Ruthenium CatalystsAccuray of the Computational MethodsINTERMEDIATES IN OLEFIN METATHESISIntroductionMetathesis-Active, Early-Metal MetallacyclesIntermediates in Ruthenium-Catalyzed Olefin MetathesisFuture DirectionsFACTORS AFFECTING INITIATION RATESIntroductionGrubbs Second-Generation CatalystGrubbs-Hoveyda-Type PrecatalystsPyridine SolvatesPiers CatalystsIndenylidene Carbene PrecatalystsZ-Selective CatalystsHerrmann-Type, BisNHCsConclusionsDEGENERATE METATHESISIntroductionDegenerate Metathesis MechanismsDegenerate Metathesis with Early Transition-Metal CatalystsDegenerate Metathesis with Ruthenium CatalystsBeneficial Effects of Degenerate MetathesisConclusionsMECHANISMS OF OLEFIN METATHESIS CATALYST DECOMPOSITION AND METHODS OF CATALYST REACTIVATIONIntroductionDecomposition of Mo and W Imido Alkylidene Catalysts and Related ComplexesDecomposition of Ru Alkylidene Catalysts and Related ComplexesConclusionsSOLVENT AND ADDITIVE EFFECTS ON OLEFIN METATHESISGeneral IntroductionSolvent Effects on Olefin MetathesisAdditive Effects on Olefin MetathesisSummaryMETATHESIS PRODUCT PURIFICATIONIntroductionChromatographic and Chemical Removal of RutheniumRemoval by ComplexationConclusionRUTHENIUM INDENYLIDENE CATALYSTS FOR ALKENE METATHESISIntroductionThe Initial Development of Indenylidene Metal Complexes for Alkene MetathesisBinuclear Indenylidene Ruthenium Catalysts Arising from Ruthenium(arene) ComplexesPreparation of Ruthenium Indenylidene Catalysts from RuCl2(PPh3)3Ruthenium Catalysts Bearing a Chelating Indenylidene LigandConclusion
About the author
Robert H. Grubbs received his Ph.D. from Columbia University for work with Ron Breslow. After a postdoctoral year with Jim Collman at Stanford University, he joined the faculty at Michigan State University. In 1978, he moved to the California Institute of Technology, where he is now the Victor and Elizabeth Atkins Professor of Chemistry. Among many other awards, he received the Nobel Prize in 2005 for his research on the metathesis reaction. His research interests include polymer chemistry, organometallic catalysis, and the development of new synthetic organic methodology.
Anna G. Wenzel received her PhD at Harvard University under the guidance of Prof. E. N. Jacobsen. From 2003 to 2006, she joined the group of Prof. R. H. Grubbs as an NIH Postdoctoral Scholar. In 2006, she joined the faculty as an Assistant Professor at the W. M. Keck Science Department in Claremont, California. In 2012, she was promoted to Associate Professor. Her research topics are asymmetric catalysis, organometallic chemistry, and organic synthesis.
Summary
The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality.
Edited by the Nobel laureate R. H. Grubbs and A. G. Wenzel, this volume 1 of the 3-volume work focusses on catalyst development and mechanism. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry.
Other available volumes:
Volume 2: Applications in Organic Synthesis, Editors: R. H. Grubbs and D. J. O´Leary
Volume 3: Polymer Synthesis, Editors: R. H. Grubbs and E. Khosravi
