Apoptosis related proteins p53 and Bcl-2 in hepatocellular carcinoma

Hepatitis B virus and hepatitis C virus may be involved in hepatocarcinogenesis in patients with HCC. These viral infections may be responsible, at least in a part, for the mutational change in the p53 gene and may affect the expression of the Bcl-2 protein in HCC patients. p53 and Bcl-2 proteins overexpression was detected in serum and tissues in HCC patients positive for hepatitis B or C or both and this overexpression was more frequently associated with HBV infection than HCV infection.

About the author

Dr. Entsar A. Saad is Associate Professor of Biochemistry at Damietta University (Egypt). She completed her under and graduate studies with a Ph.D. from Mansoura University (Egypt). She is a member of the Egyptian Society of Biochemistry and Molecular Biology.

Product details

• Authors: Hoda El-Emshaty, Entsa Saad, Entsar Saad, El-Shaha Toson, El-Shahat Toson
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 01.01.2014
• EAN: 9783659611117
• ISBN: 978-3-659-61111-7
• No. of pages: 292
• Subject: Natural sciences, medicine, IT, technology > Chemistry > Miscellaneous