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Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.
List of contents
Historical perspectives in understanding traumatic brain injury and in situating disruption in CBF in the pathotrajectory of head trauma.- Situating Cerebral Blood Flow in the Pathotrajectory of Head Trauma.- Modeling of traumatic brain injury and its implications in studying the pathology of repeated mild impacts to the head.- The presence of venous damage and microbleeds in traumatic brain injury and the potential future role of angiographic and perfusion magnetic resonance imaging.- Situating the Endothelin System in the pathotrajectory of TBI-induced changes in haemodynamics.- Age and Sex Differences in Cerebral Blood Flow and Autoregulation after Pediatric Traumatic Brain Injury.- New Frontiers in Clinical Trials Aimed at Improving Outcome Following Traumatic Brain Injury.
Summary
Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.
