Reaction monitoring by DPPH - M.Pharm. (PharmChem) student Mr. Viraj P. Jatakiya did the project under the guidance of Dr. D.J. Sen & Dr. R.Badmanaban

The project work focuses on the organic reaction monitoring by DPPH on the synthesised eight compounds of two series having variable electronegative atoms X=O/S/NH which have been screened for CNS depression study by synergistic activity by standard drug. This project is a comparison between the SAR study with antioxidant potentiality by DPPH by using logP values with IC50 values with lambda max in UV.The logP value of 4-carboxamido phenyl thio urea (-0.31) is lesser than 2-carboxy phenyl thiourea (1.53) , so the same property arises during potentiality of lmax in UV. The logP value of 4-carboxy phenyl thiourea (0.84) is greater than 2-carboxamido phenyl urea (0.47), so antioxidant potentiality of IC50 value for 2-carboxamido phenyl urea is -661.18 ppm which is more effective than 4-carboxy phenyl thiourea which is 43.79 ppm.

About the author

Eminent scholar cum researcher Prof. Dr. Dhrubo Jyoti Sen is at present working as a Professor of Pharmaceutical & Medicinal chemistry in School of Pharmacy, Techno India University, Kolkata, West Bengal, India is working in academic field from more than two decades and has published more than 600 research/review papers in peer reviewed journals.

Product details

• Authors: R Badmanaban, R. Badmanaban, Viraj Jatakiya, Viraj P Jatakiya, Viraj P. Jatakiya, Dhrubo Jyot Sen, Dhrubo Jyoti Sen
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 10.01.2012
• EAN: 9783847325413
• ISBN: 978-3-8473-2541-3
• No. of pages: 80
• Subject: Natural sciences, medicine, IT, technology > Medicine > Pharmacy