SYNTHESIS OF COMPOUNDS CONTAINING 9(10H)-ACRIDONE - SYNTHESIS OF SOME NEW HETEROCYCLIC COMPOUNDS CONTAINING 9(10H)-ACRIDONE, AND STUDYING THEIR BIOLOGICAL ACTIVITY

Acridone derivatives containing 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole rings are synthesized.Diphenylamine-2,4`-dicarboxylic acid [1] is obtained in a high yield by refluxing a mixture of 4-aminobenzoic acid and 2-chloro benzoic acid in the presence of catalytic amount of copper oxide. 9(10H)-Acridone-2-carboxylic acid [2] is synthesized in ring closure reaction by heating compound [1] in sulfuric acid followed by basic hydrolysis.Reaction of compound [2] with thiosemicarbazide in the presence of phosphorus oxychloride gave 2-[5-amino-1, 3, 4-thiadiazole-2-yl]-9(10H)-acridone

About the author

Ayad Hameed, Emad Yousif and Ayad Kreem, Department of Chemistry,College of Science, AL-Nahrain University, Baghdad, Iraq. JumatSalimon and Nadia Salih,School of Chemical Science and FoodTechnology, Faculty of Science and Technology, UniversitiKebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

Product details

• Authors: Aya Hameed, Ayad Hameed, Ayad Kreem, Ema Yousif, Emad Yousif
• Publisher: LAP Lambert Academic Publishing
• Languages: English, German
• Product format: Paperback / Softback
• Released: 08.06.2011
• EAN: 9783844327861
• ISBN: 978-3-8443-2786-1
• No. of pages: 88
• Subject: Natural sciences, medicine, IT, technology > Chemistry > Organic chemistry