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Informationen zum Autor Professor Robert K Poole is Emeritus Professor of Microbiology at the University of Sheffield, UK. He was previously West Riding Professor of Microbiology at Sheffield and until 1996 held a Personal Chair in Microbiology at King’s College London. During his long career, he has been awarded several research Fellowships, and taken sabbatical leave at the Australian National University, Kyoto University and Cornell University. His career-long interests have been in the areas of bacterial respiratory metabolism, metal-microbe interactions and bioactive small gas molecules. In particular, he has made notable contributions to bacterial terminal oxidases and resistance to nitric oxide with implications for bacterial pathogenesis. He co-discovered the flavohaemoglobin Hmp, now recognised as the preeminent mechanism of nitric oxide resistance in bacteria. He has served as Chairman of numerous research council grant committees, held research grants for over 40 years and published extensively (h-index, 2024 = 70). He served on several Institute review panels in the UK and overseas. He is a Fellow of the Royal Society of Chemistry and the Royal Society of Biology. Klappentext This volume is an up-to-date overview of the physiology of selected pathogenic bacteria. Each chapter is written by experts in the field of that organism.The focus is on biochemistry and physiology but topics of clinical relevance are included. Inhaltsverzeichnis 1. Energetics of Pathogenic Bacteria and Opportunities for Drug Development Gregory M. Cook, Chris Greening, Kiel Hards and Michael Berney 2. The Impact of Horizontal Gene Transfer on the Biology of Clostridium difficile Adam P. Roberts, Elaine Allan and Peter Mullany 3. Metal Ion Homeostasis in Listeria monocytogenes and Importance in Host-Pathogen Interactions Helen E. Jesse, Ian S. Roberts and Jennifer S. Cavet 4. The Role of Macrophages in the Innate Immune Response to Streptococcus pneumoniae and Staphylococcus aureus ; Mechansims and Contrasts Joby Cole, Jody Aberdein, Jamil Jubrail and David H. Dockrell 5. Aeromonas Flagella and Colonisation Mechanisms Rebecca Lowry, Sabela Balboa, Jennifer L. Parker and Jonathan G. Shaw 6. Physiological Adaptations of Key Oral Bacteria Ian Douglas, Kate Naylor, Chatchawal Phansopa, Andrew Frey, Thomas Farmilo and Graham P Stafford 7. Virulence Factors of Uropathogenic E. coli and their Interaction with the Host Petra Lüthje and Annelie Brauner ...
List of contents
1. Energetics of Pathogenic Bacteria and Opportunities for Drug Development
Gregory M. Cook, Chris Greening, Kiel Hards and Michael Berney
2. The Impact of Horizontal Gene Transfer on the Biology of Clostridium difficile
Adam P. Roberts, Elaine Allan and Peter Mullany
3. Metal Ion Homeostasis in Listeria monocytogenes and Importance in Host-Pathogen Interactions
Helen E. Jesse, Ian S. Roberts and Jennifer S. Cavet
4. The Role of Macrophages in the Innate Immune Response to Streptococcus pneumoniae and Staphylococcus aureus; Mechansims and Contrasts
Joby Cole, Jody Aberdein, Jamil Jubrail and David H. Dockrell
5. Aeromonas Flagella and Colonisation Mechanisms
Rebecca Lowry, Sabela Balboa, Jennifer L. Parker and Jonathan G. Shaw
6. Physiological Adaptations of Key Oral Bacteria
Ian Douglas, Kate Naylor, Chatchawal Phansopa, Andrew Frey, Thomas Farmilo and Graham P Stafford
7. Virulence Factors of Uropathogenic E. coli and their Interaction with the Host
Petra Lüthje and Annelie Brauner
Report
"This series has consistently presented a well balanced account of progress in microbial physiology...invaluable for teaching purposes." --American Scientist