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The present work describes synthesis of copper alginate-cotton cellulose and chitosan attached cotton composite fibers and detailed investigation of antimicrobial action against the model bacteria E.coli. The fibers were prepared by different techniques. The resulting fibers were investigated for their biocidal action against E.coli, by using zone inhibition and colonies counting method. Finally, fibers were reduced with sodium borohydride to yield copper nanoparticles- loaded composite fibers and investigated for biocidal action. It was found that these fibers possessed both, the fair mechanical strength and antibacterial action. The extent of biocidal action was found to depend upon the amount of Cu(II) loaded and concentration of alginate into cotton- cellulose fibers. The fibers showed higher Cu(II) release in physiological fluid as compared to distilled water. Copper alginate-cotton cellulose (CACC) fibers show fair mechanical strength and release copper ions in the presence of physiological fluid and protein solution. These fibers have great potential to be used as dressing materials.
About the author
Dr.S.K. Bajpai obtained his Ph.D degree in the year 1997 and haspublished about 95 papers in various international journals.His research area include drug delivery,nanotechnology,antimicrobialfiber and fabrics.He is regular referee of a number ofjournals.He has edited a book on Recent advances innanotechnology, and also authored a book chapter.
