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The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num hering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the in tellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explo sion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an in valuable reference a·nd sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
List of contents
1 Structure of Viral Nucleic Acids in Situ.- 1. Viruses with Single-Stranded Nucleic Acids.- 2. Viruses with Double-Stranded DNA.- 3. Concluding Remarks.- 4. References.- 2 Structure of Small DNA-Containing Animal Viruses.- 1. General Principles of Virus Structure.- 2. Papilloma Viruses.- 3. SV40 and Polyoma Virus.- 4. References.- 3 Pseudovirions in Animals, Plants, and Bacteria.- 1. Introduction.- 2. Animal Cell Pseudovirions.- 3. Plant Cell Pseudovirions (Tobacco Mosaic Pseudovirions).- 4. Bacterial Cell Pseudovirions (Generalized Transducing Phages).- 5. Orphan Pseudovirions.- 6. Possible Biological Roles of Pseudovirions.- 7. Summary.- 8. References.
