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Zusatztext The book is well written by experts from each of the subject fields ... and is recommended for those who want a thorough theoretical review of the field. Informationen zum Autor Dr. Michael Strong is Dean of the Schulich School of Medicine and Dentistry at the University of Western Ontario, a Distinguished University Professor and the Arthur J. Hudson Chair in ALS Research. Dr Strong is a scientist at the Robarts Research Institute, and has also served as co-chair of the Canadian ALS Research Consortium and is a former member of the Board of Directors of the ALS Society of Canada. His basic research focuses on the study of alterations in neurofilament metabolism in degenerating motor neurons in ALS and how perturbations in RNA metabolism contribute to this process. His clinical research has been central to identifying the frontotemporal syndromes of ALS. Klappentext This book summarizes the advances in our understanding of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), as well as the potential relationship between the two. Zusammenfassung This book summarizes the advances in our understanding of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), as well as the potential relationship between the two. Inhaltsverzeichnis 1: Ralph M. Garruto: Lessons from the study of natural experiments of hyperendemic foci of neurodegeneration 2: Jeffrey Rosenfeld: The motor neurone diseases 3: Shigeki Kuzuhara and Yasumasa Kokubo: Amyotrophic lateral sclerosis-Pakinsonism-Dementia complex in the Kii peninsula of Japan (Muro disease): a review on recent research and new concept 4: Alexandre Henri-Bhargava and Morris Freedman: The frontotemporal dementias: an overview 5: J. B. Orange and A. E. Hillis: Language profiles in amyotrophic lateral sclerosis 6: Hiroo Ichikawa, Sotaro Hieda, Hideki Ohno, Kenji Ishihara, and Mitsuru Kawamura: Language impairment in amyotrophic lateral sclerosis from an historical review: kana and kanji versus alphabetical languages 7: Mitsuru Kawamura and Hiroo Ichikawa: Amyotrophic lateral sclerosis with dementia: neuropsychological aspects 8: Sharon Abrahams and Christopher Kipps: Social cognition in frontotemporal dementia and amyotrophic lateral sclerosis 9: Laura H. Goldstein: Behavioural change in amyotrophic lateral sclerosis 10: Jennifer Murphy, Fizaa Ahmed, and Catherine Lomen-Hoerth: Cognition in amyotrophic lateral sclerosis 11: Vincenzo Silani, Barbara Poletti, and Stefano Zago: Frontotemporal syndromes of primary lateral sclerosis 12: Jeremy M. Shefner: Electrophysiological evaluation of lower motor neurone loss in amyotrophic lateral sclerosis 13: Jan Kassubek and Albert C. Ludolph: Multimodality approach to neuroimaging in amyotrophic lateral sclerosis/frontotemporal dementia 14: Sandra E. Black and Yana Yunusova: Using neuroimaging to understand brain-behaviour relationships in the context of motor neurone disease 15: S. Kalra: Amyotrophic lateral sclerosis and the frontotemporal dementias: using neuroimaging to quantitate disease progression 16: Tiffany W. Chow: Differentiating normal from pathological atrophy: when is frontotemporal atrophy normal? 17: Robert Bowser, James Connor, and Martin Turner: Cerebrospinal fluid-based biomarkers for amyotrophic lateral sclerosis 18: Nigel J. Cairns: Neuropathology of frontotemporal lobar degeneration 19: J. Robin Highley and Paul G. Ince: The neuropathology of the motor neurone diseases 20: Bryan J. Traynor and Stuart Pickering-Brown: Genetics of frontotemporal dementia 21: Ashley Jones and Ammar Al-Chalabi: Genetics of the MNDs 22: Kathryn Volkening and Michael J. Strong: Perturbed RNA metabolism in amyotrophic lateral sclerosis 23: Michael J. Strong, Wencheng Yang, May Gohar, and Wendy L. Strong: Alterations in tau metabolism in amyotrophic lateral sclerosis with cognitive ...
