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Klappentext In this book, an international team of authors outline the neurochemistry, drug development, and clinical use of botulinum toxins. Zusammenfassung Botulinum toxins play a very significant role in the management of many medical conditions! from spasticity to sweating. In this book! an international team of authors outline the neurochemistry! drug development! and clinical use of botulinum toxins for an audience of neuroscientists! neurologists! dermatologists! pediatricians! plastic surgeons and rehabilitation specialists. Inhaltsverzeichnis 1. Introduction Michael Barnes and Anthony Ward; 2. Mechanistic basis for the therapeutic effectiveness of botulinum toxin A on over-active cholinergic nerve Oliver Dolly and Gary Lawrence; 3. Botulinum toxin: from menace to medicine Peter Hambleton, Andrew Pickett and Clifford Shone; 4. Botulinum toxin: primary and secondary resistance Benjamin Anyanwu, Philip Hanna and Joseph Jankovic; 5. Introduction to botulinum toxin and clinical practice Anthony Ward; 6. Cervical dystonia Khalid Anwar; 7. The use of botulinum toxin in otolaryngology Maurice Hawthorne and Khalid Anwar; 8. Spasticity Anthony Ward; 9. Hyperhidrosis Deeanna Glaser; 10. Hypersalivation Fiorella Contarino, Alberto Albanese; 11. Botulinum toxin type A for the prophylactic treatment of primary headache disorders David Dodick; 12. Botulinum toxin in the management of back and neck pain Áine Carroll; 13. Ophthalmological uses of botulinum toxin John Elston; 14. Bladder and bowel indications Guiseppe Brisinda, Federica Cadeddu and Giorgio Maria; 15. Cosmetic uses of botulinum toxin type A Alastair Carruthers and Ken Beer; 16. Other clinical neurological uses of botulinum toxin Michael Barnes.