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Informationen zum Autor Edited by Christopher D. Byrne, FRCP, FRCPath, PhD, Institute for Developmental Sciences, Southampton General Hospital, Southampton, UK Sarah H. Wild, FRCPE, FFPH, PhD, Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK Klappentext The Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. This book explains the aetiology, pathogenesis and clinical treatment of all risk factors as well as the relationship with diabetes, non alcoholic fatty liver disease, polycystic ovary syndrome and coronary heart disease.The Metabolic Syndrome has been further improved from the 1st edition that was highly commended in 2006 Annual British Medical Association medical books competition. All chapters from the first edition are fully updated and this new edition contains an increase in international contributions and five new chapters on:* Childhood obesity and metabolic syndrome* Bariatric surgery for obesity* Fitness* Brain insulin resistance and appetite* The nature of the insulin resistance seen in metabolic syndrome.This brand new edition of The Metabolic Syndrome will be an indispensable resource for all clinical researchers, physicians and scientists requiring detailed up-to-date information on the metabolic syndrome to further their own research or to treat and manage the syndrome and its complications. Specifically, the text will be of particular relevance to those involved and working in the fields of diabetes, endocrinology, obesity, cardiology, vascular disease and hepatology. Zusammenfassung The Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. Inhaltsverzeichnis List of Contributors vii Foreword, Professor Sir George Alberti xi Preface xiii 1 The Epidemiology of the Metabolic Syndrome and its Association with Diabetes, Cardiovascular Disease and Other Conditions 1 Sarah H. Wild and Christopher D. Byrne 2 Metabolic Syndrome and Ethnicity 19 Therese Tillin and Nita G. Forouhi 3 Developmental Origins of Endothelial Dysfunction: a Key Step in Cardiometabolic Disease 45 Christopher Torrens, Geraldine F. Clough and Mark A. Hanson 4 Developmental Origins of Insulin Resistance and Type 2 Diabetes 60 Susan E. Ozanne and Kenneth Siddle 5 The Metabolic Syndrome in Childhood 81 Ram Weiss and Sonia Caprio 6 Assessment of Insulin Sensitivity 88 Julia Szendroedi, Esther Phielix and Michael Roden 7 Recent Progress in Identifying Genes Contributing to Type 2 Diabetes and Metabolic Syndrome 106 Weijia Xie, Timothy M. Frayling and Michael N. Weedon 8 Endocrine Aspects of the Metabolic Syndrome 120 Richard I.G. Holt and Peter H. Sönksen 9 Brain Insulin Resistance 139 Katharine F. Hunt, Yee Seun Cheah and Stephanie A. Amiel 10 Cardiorespiratory Fitness and the Metabolic Syndrome 165 Paul A. McAuley and Steven N. Blair 11 Metabolic Syndrome and Mental Illness 177 Richard I.G. Holt and Robert C. Peveler 12 Atherothrombosis and the Metabolic Syndrome 194 Kristina F. Standeven and Peter J. Grant 13 Inflammation and Metabolic Syndrome 210 Sridevi Devaraj, David Siegel and Ishwarlal Jialal 14 Adipocytokine Dysregulation, Obesity and the Metabolic Syndrome 229 Ulf Smith and Xiaolin Yang 15 Non-Alcoholic Fatty Liver Disease 245 Mohamed H. Ahmed and Christopher D. Byrne 16 Polycystic Ovary Syndrome 278 Naveed Sattar 17 Nutrition: Its Relevance in Development and Treatment o...
