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Klappentext Over the last decades! a series of dramatic research findings have served to emphasize the vital role of the peroxisome. These findings have included major advances in our understanding of its metabolic roles! genetics and biochemistry! as well as of the broad involvements of peroxisomal diseases. This book provides a basic introduction to the peroxisome and its relationship to other components of eukaryotic cells! followed by a detailed and comprehensive discussion of research advances. Current understanding of the morphology! phylogeny! enzymology and ontogeny of the peroxisome is also reviewed. The book concludes with a chapter on peroxisomes and human disease. The authors are well-respected researchers in this field! and have produced an authoritative and readable text which will appeal to postgraduates and researchers in biochemistry! cell biology and medical science. Zusammenfassung Knowledge of the peroxisome has advanced extremely rapidly in recent years. This book provides authoritative and readable coverage of the role of the peroxisome in normal cellular function and human peroxisomal diseases. It will appeal to postgraduates and researchers in this and related fields. Inhaltsverzeichnis Preface; 1. Introduction; 2. Enzymology; 3. Intraparticulate organization of peroxisomal proteins - methodology and topology; 4. The phenotypic characteristics, genetics and ontogeny of peroxisomal proteins; 5. Peroxisomal metabolism - lipids; 6. Further metabolic involvements of the peroxisome; 7. Regulatory factors in peroxisomal metabolism; 8. Peroxisomal biogenesis and turnover; 9. Peroxisome proliferators; 10. Peroxisomes and human disease; 11. Concluding comments; Bibliography; Index.
