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Klappentext This specialized volume of Advances in Cancer Research is dedicated to the complex and largely unexplored field of intratumor diversity, with respect to differences in both genotype and phenotype among cell populations within tumors. Zusammenfassung Informs readers on novel findings as well as gives a historical perspective to the field. This title offers a starting point for young scientists entering this field of research. Inhaltsverzeichnis Introduction Role of telomere dysfunction in genetic intratumour diversity How mitotic errors contribute to karyotypic diversity in cancer Nuclear Remodelling as a Mechanism for Genomic Instability in Cancer Cytogenetic Analysis of Tumor Clonality Genotyping techniques to address diversity in tumors Prostate Cancer as a Model System for Genetic Diversity in Tumours Evolutionary mechanisms and diversity in cancer Cancer stem cells in tumor heterogeneity Cancer: Beyond Speciation
List of contents
- Introduction
- Role of telomere dysfunction in genetic intratumour diversity
- How mitotic errors contribute to karyotypic diversity in cancer
- Nuclear Remodelling as a Mechanism for Genomic Instability in Cancer
- Cytogenetic Analysis of Tumor Clonality
- Genotyping techniques to address diversity in tumors
- Prostate Cancer as a Model System for Genetic Diversity in Tumours
- Evolutionary mechanisms and diversity in cancer
- Cancer stem cells in tumor heterogeneity
- Cancer: Beyond Speciation
