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Research on dyneins has a direct impact on human diseases, such as viruses and cancer. Suitable for researchers and clinicians across developmental biology, cell biology, genetics and medicine, this title covers the structure, biology and application of dynein research to human disease. Inhaltsverzeichnis I History and Evolution Chapter 1 Discovery of Dynein and its Properties : A Personal Account Chapter 2 Evolutionary Biology of Dyneins II Structure and Mechanics of Dynein Motors Chapter 3 The AAA+ Powerhouse-Trying to Understand How it Works Chapter 4 Dynein Motor Mechanisms Chapter 5 Structural Analysis of Dynein Intermediate and Light Chains Chapter 6 Biophysics of Dynein In Vivo III Dyneins in Ciliary Biology Chapter 7 Composition and Assembly of Axonemal Dyneins Chapter 8 Organization of Dyneins in the Axoneme Chapter 9 Genetic Approaches to Axonemal Dynein Function in Chlamydomonas and Other Organisms Chapter 10 Regulation of Axonemal Outer-Arm Dyneins in Cilia Chapter 11 Control of Axonemal Inner Dynein Arms Chapter 12 Flagellar Motility and the Dynein Regulatory Complex Chapter 13 Regulation of Dynein in Ciliary and Flagellar Movement Chapter 14 Dynein and Intraflagella Transport IV Cytoplasmic Dynein Biology Chapter 15 Cytoplasmic Dynein Function Define by Subunit Composition Chapter 16 Studies of Lissencephaly and Neurodegenerative Disease Reveal Novel Aspects of Chapter 17 Insights into Cytoplasmic Dynein Function and Regulation from Fungal Genetics Chapter 18 Genetic Insights in to Mammalian Cytoplasmic Dynein Function Provided by Novel Mutations in Mouse Chapter 19 Role of Dynactin in Dynein-mediated Motility Chapter 20 Roles of Cytoplasmic Dynein during Mitosis V Dynein Dysfunction and Disease Chapter 21 Does Dynein Influence the Non -Mendelian Inheritance of Chromosome 17 Homologs in Male Mice? Chapter 22 Role of Dynein in Viral Pathogenesis Chapter 23 Cytoplasmic Dynein Dysfunction and Neurodegenerative Disease Chapter 24 Dynein Dysfunction as a Cause of Primary Ciliary Dyskinesia and Other Ciliopathies ...
List of contents
I History and Evolution
Chapter 1 Discovery of Dynein and its Properties : A Personal Account
Chapter 2 Evolutionary Biology of Dyneins
II Structure and Mechanics of Dynein Motors
Chapter 3 The AAA+ Powerhouse-Trying to Understand How it Works
Chapter 4 Dynein Motor Mechanisms
Chapter 5 Structural Analysis of Dynein Intermediate and Light Chains
Chapter 6 Biophysics of Dynein In Vivo
III Dyneins in Ciliary Biology
Chapter 7 Composition and Assembly of Axonemal Dyneins
Chapter 8 Organization of Dyneins in the Axoneme
Chapter 9 Genetic Approaches to Axonemal Dynein Function in Chlamydomonas and Other Organisms
Chapter 10 Regulation of Axonemal Outer-Arm Dyneins in Cilia
Chapter 11 Control of Axonemal Inner Dynein Arms
Chapter 12 Flagellar Motility and the Dynein Regulatory Complex
Chapter 13 Regulation of Dynein in Ciliary and Flagellar Movement
Chapter 14 Dynein and Intraflagella Transport
IV Cytoplasmic Dynein Biology
Chapter 15 Cytoplasmic Dynein Function Define by Subunit Composition
Chapter 16 Studies of Lissencephaly and Neurodegenerative Disease Reveal Novel Aspects of
Chapter 17 Insights into Cytoplasmic Dynein Function and Regulation from Fungal Genetics
Chapter 18 Genetic Insights in to Mammalian Cytoplasmic Dynein Function Provided by Novel Mutations in Mouse
Chapter 19 Role of Dynactin in Dynein-mediated Motility
Chapter 20 Roles of Cytoplasmic Dynein during Mitosis
V Dynein Dysfunction and Disease
Chapter 21 Does Dynein Influence the Non -Mendelian Inheritance of Chromosome 17 Homologs in Male Mice?
Chapter 22 Role of Dynein in Viral Pathogenesis
Chapter 23 Cytoplasmic Dynein Dysfunction and Neurodegenerative Disease
Chapter 24 Dynein Dysfunction as a Cause of Primary Ciliary Dyskinesia and Other Ciliopathies
