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Zusatztext According to the back cover of this excellent book, the target readership includes a diverse range of scientists. In my opinion, the authors have succeeded brilliantly in this aim; [...] the book provides not only the key basic facts, but also provides the reader with the essential information to investigate further. The book is timely and informative and certainly ought to be widely read by a range of different scientists with interests in macromolecular structure. Informationen zum Autor Naomi E. Chayen is Professor of Biomedical Sciences at Imperial College London, Visiting Professor at Harvard Medical School and the President of the International Organisation for Biological Crystallization (IOBCr). She organises and chairs crystallization sessions at international conferences and courses, and is a Crystallization Co-Editor of Acta Crystallographica D.Prof J R Helliwell is Professor of Structural Chemistry at the University of Manchester and an Honorary Visiting Scientist at the STFC Daresbury Laboratory. He has served as Editor-in-Chief of Acta Crystallographica and is currently President of the European Crystallographic Association.Dr Edward Snell is Assistant Professor at the Hauptman-Woodward Medical Research Institute at the State University of New York at Buffalo. He has worked at NASA as a senior scientist and was PI on several space missions on the International Space station. He has received a number of academic awards. Klappentext Structural biology is key to our understanding of the mechanisms of biological processes. This book describes current methods and future frontiers in crystal growth and use of X-ray and Neutron crystallography, in the context of the very successful current automation of crystallization and generation of synchrotron X-ray and neutron beams. Zusammenfassung Structural biology is key to our understanding of the mechanisms of biological processes. This book describes current methods and future frontiers in crystal growth and use of X-ray and Neutron crystallography, in the context of the very successful current automation of crystallization and generation of synchrotron X-ray and neutron beams. Inhaltsverzeichnis I: INTRODUCTION AND OVERVIEW 1: Introduction II: CRYSTALLIZATION 2: Crystallization Theory 3: Practical Methods of Crystallization 4: Screening 5: Optimization 6: Strategies when high quality crystals cannot be obtained 7: Membrane Proteins 8: Alternative Approaches III: DIFFRACTION 9: Experimental Aspects 10: Analysis of the Molecular Short-Range Order 11: Analysis of the Long-Range Order 12: Macromolecular Crystals and Twinning 13: Other Macromolecular Crystal Diffraction Disorders 14: Degradation and Improvement of Crystal Perfection 15: Unusual Diffraction Geometries 16: Making the Most of Difficult Crystals 17: Protein Powders 18: Complementary Techniques IV: THE FUTURE 19: The X-ray Laser and the Single Molecule 20: Overall Summary and Future Thoughts Glossary of Abbreviations, Terms, and Symbols References Index ...
