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Informationen zum Autor ADRIAN BOT is Senior Director of Scientific Management and Acting Head of Translational Medicine at MannKind Corporation! in Valencia! California. He obtained his M.D. at the University of Medicine and Pharmacy in Timisoara! Romania and his Ph.D. in Biomedical Sciences at Mount Sinai School of Medicine in New York. He previously held appointments at the Scripps Research Institute and Alliance Pharmaceutical Corporation in San Diego. Dr. Bot authored more than one hundred publications and patents in oncology! vaccines! drug delivery technologies and immunotherapy. He is the Editor-in-Chief of the International Reviews of Immunology and has been on advisory boards of several organizations.MIHAIL OBROCEA is Vice President! Clinical Development! MannKind Corporation! Paramus! New Jersey. Dr. Obrocea received his M.D. from the Faculty of Medicine and Pharmacy! Bucharest! Romania. He is a medical oncologist with over 10 years of academic and industry experience in oncology clinical trials! including biologic agents! small molecules and cytotoxic agents. Dr. Obrocea has published in oncology peer-reviewed literature! and has various patents in the field of biotechnology. Klappentext Cancer Vaccines Zusammenfassung Cancer Vaccines Inhaltsverzeichnis SECTION I - Basic Aspects: Tumor Antigens and Preclinical Modelling1. Factoring in antigen processing in designing anti-tumor T-cell vaccines! Lévy! Colombetti! Janda! Chapatte! Alves! Casado! Lévy and Peitrequin2. Outlining the gap between preclinical models and clinical situation! Daniel L. LeveySECTION II - Cell Based! Anti-infectious and Personalized Vaccines3. THERAPEUTIC AND PROPHYLACTIC CANCER VACCINES - EMERGING PERSPECTIVES FROM ALLOGENEIC AND INFECTIOUS DISEASE VACCINES! Srinivasan4. Personalized Cancer Vaccines! Teofilovici! Wentworth5. Dendritic cell vaccines for gliomas! Luptrawan! Liu! S. Yu and BrianIII. INTRACEREBRAL HEMORRHAGE (ICH)6. Peptide based active immunotherapy in cancer! Schroter and Minev7. Multimodality Immunization Approaches to Improve on DNA Vaccines for Cancer! Qiu and Smith8. Bidirectional Bedside Lab Bench Processes and Flexible Trial Design as a Means to Expedite the Development of Novel Immunotherapeutics! Bot and Obrocea9. Diagnostic approaches for selecting patient-customized therapies! obviating tumor variability to maximize therapeutic effect! Chang! Kertesz! Liu ...