Heparin - A Century of Progress

Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

List of contents

Part 1. Introduction.- Part 2. Unfractionated and Low Molecular Weight Heparins.- Part 3. Clinical Use of Heparin and LMWH.- Part 4. Non Anticoagulant Indictions for Heparin and Related Compounds.- Part 5. Heparin-like Entities.

Summary

Heparins remain amongst the most commonly used drugs in clinical practice.  Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

Product details

• Assisted by: Rebecca Lever (Editor), Barbar Mulloy (Editor), Barbara Mulloy (Editor), Clive P Page (Editor), Clive P. Page (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 20.06.2014
• EAN: 9783642434587
• ISBN: 978-3-642-43458-7
• No. of pages: 462
• Dimensions: 155 mm x 25 mm x 235 mm
• Weight: 724 g
• Illustrations: XIV, 462 p.
• Series: Handbook of Experimental Pharmacology; Handbook of Experimental Pharmacology
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Pharmacy; C, Medical research, INTERNAL MEDICINE, Hematology, molecular biology, Pharmacology, Biomedical and Life Sciences, Biomedical Research, Clinical & internal medicine, Industrial chemistry & chemical engineering, Pharmaceutical technology, Pharmaceutics, Pharmaceutical Sciences/Technology, Molecular Medicine, Haematology, Pharmacology/Toxicology