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Proliposome technologies are stable phospholipid formulations that provide an approach to generating liposomes upon addition of aqueous phase prior to administration. In this monograph, the authors review the potential of proliposomes for pulmonary delivery of liposomes via nebulization using air-jet, ultrasonic and vibrating-mesh nebulizers. They explore both proliposome types, particulate-based and solvent-based. The book concludes that both types are capable of exploiting the energy of nebulization to generate liposomes within nebulizers.
List of contents
Introduction.- Methodology.- Studies on Particulate-based proliposomes.- Studies on solvent (alcohol) based proliposomes.
About the author
Waqar Ahmed is Director of the Institute of Advanced Manufacturing and Innovation at the School of Computing, Technology and Applied Sciences of the University of Central Lancashire, UK. He obtained his PhD in Chemistry from the University of Salford/Strathclyde and holds a certificate in business administration from the University of Warwick. Before pursuing his academic career he worked as an engineer and operations manager in various British companies. Waqar Ahmed acts as editor-in-chief for four international journals devoted to nanomanufacturing and biomaterials and as vice-president of the Society of Nanoscience & Nanotechnology.
Summary
Proliposome technologies are stable phospholipid formulations that provide an approach to generating liposomes upon addition of aqueous phase prior to administration. In this monograph, the authors review the potential of proliposomes for pulmonary delivery of liposomes via nebulization using air-jet, ultrasonic and vibrating-mesh nebulizers. They explore both proliposome types, particulate-based and solvent-based. The book concludes that both types are capable of exploiting the energy of nebulization to generate liposomes within nebulizers.