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Organocatalyzed Reactions I and II presents a timely summary of organocatalysed reactions including: a) Enantioselective C-C bond formation processes e.g. Michael-addition, Mannich-reaction, Hydrocyanation (Strecker-reaction), aldol reaction, allylation, cycloadditions, aza-Diels-Alder reactions, benzoin condensation, Stetter reaction, conjugative Umpolung, asymmetric Friedel-Crafts reactions; b) Asymmetric enantioselective reduction processes e.g. Reductive amination of aldehydes or ketones, asymmetric transfer hydrogenation; c) Asymmetric enantioselective oxidation processes;
d) Asymmetric epoxidation, Bayer-Villiger oxidation; e) Enantioselective a-functionalization; f) A-alkylation of ketones, a-halogenation and a-oxidation of carbonyl compounds.
List of contents
Organocatalytic Cyclisations.- Organocatalyzed Conjugate Additions.- Organocatalyzed Cycloadditions.- Organocatalyzed Aldoladditions.- Organocatalyzed Domino-Reactions.- Organocatalyzed Mannich-Reactions.
About the author
Dr. Rainer Mahrwald was born in 1950. He studied chemistry at MLU Halle and subsequently joined the Manfred von Ardenne Research Institute in Dresden, where he led the synthetics group. He gained his doctorate under G. Wagner in Leipzig in 1979, and went on to the Institute of Organic Chemistry at the Academy of Science in Berlin, where he remained until 1990. Following a stay at the Philipps-University in Marburg, Dr. Mahrwald qualified as a lecturer at the Humboldt University Berlin, where he is now a lecturer.
Summary
Organocatalyzed Reactions I and II presents a timely summary of organocatalysed reactions including: a) Enantioselective C-C bond formation processes e.g. Michael-addition, Mannich-reaction, Hydrocyanation (Strecker-reaction), aldol reaction, allylation, cycloadditions, aza-Diels-Alder reactions, benzoin condensation, Stetter reaction, conjugative Umpolung, asymmetric Friedel-Crafts reactions; b) Asymmetric enantioselective reduction processes e.g. Reductive amination of aldehydes or ketones, asymmetric transfer hydrogenation; c) Asymmetric enantioselective oxidation processes;
d) Asymmetric epoxidation, Bayer-Villiger oxidation; e) Enantioselective a-functionalization; f) A-alkylation of ketones, a-halogenation and a-oxidation of carbonyl compounds.
Additional text
From the reviews:
“Under Rainer Mahrwald’s guidance, the authors have gathered together hundreds of reactions, documented a wide variety of catalysts, and provided clear descriptions and schemes to illustrate the underlying mechanisms. … all of the chapters are crafted to inspire many new ideas and suggestions for the reader’s own work. … is well worthwhile for large research groups and libraries.” (Organic Chemistry Portal, March, 2012)
Report
From the reviews:
"Under Rainer Mahrwald's guidance, the authors have gathered together hundreds of reactions, documented a wide variety of catalysts, and provided clear descriptions and schemes to illustrate the underlying mechanisms. ... all of the chapters are crafted to inspire many new ideas and suggestions for the reader's own work. ... is well worthwhile for large research groups and libraries." (Organic Chemistry Portal, March, 2012)
