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Informationen zum Autor Paul Digard is a Lecturer in Virology in the Department of Pathology at the University of Cambridge! UK. Anthony A. Nash is Professor of Veterinary Pathology in the Division of Veterinary Biomedical Sciences at the University of Edinburgh! UK. Richard. E. Randall is Professor of Molecular Virology in the School of Biology at the University of St Andrews! UK Klappentext Covers the central factors that influence the pathogenicity of virus and prion infections. Zusammenfassung Virus and prion diseases are a major public health threat throughout the world. The HIV pandemic is one example of a newly emerged virus diseases! and older human viruses such as influenza still cause major health problems. This book covers the central factors that influence the pathogenicity of these infections. Inhaltsverzeichnis Preface; 1. Adaptive immune responses J. L. Whitton; 2. T-cell responses and dengue haemorrhagic fever G. Screaton and J. Mongkolsapaya; 3. The immune response to human immunodeficiency virus type 1 (HIV-1) E. Turnbull and P. Borrow; 4. Persistent RNA virus infections C. M. Dixon, L. Breakwell, G. Barry and J. K. Fazakerley; 5. Exotic virus pathogenesis S. Nichol; 6. Molecular approaches to the pathogenesis of feline coronaviruses C. Dye and S. Siddell; 7. The transmissible spongiform encephalopathies J. C. Manson and R. M. Barron; 8. Influenza virus pathogenicity R. G. Webster, A. S. Lipatov and E. Hoffmann; 9. RNAi as an antiviral mechanism and therapeutic approach R. P. van Rij and R. Andino; 10. Neurons and host immunity conspire to maintain herpes simplex virus in a latent state M. L. Freeman, V. Decman and R. L. Hendricks; 11. Hepatitis C virus disruption of interferon signalling pathways and evasion of innate intracellular antiviral defences S. M. Lemon and K. Li; 12. Human papillomaviruses and their effects on cell cycle control and apoptosis L. Gray, C. Jolly and C. S. Herrington; 13. Intracellular antiviral defence mechanisms: the power of interferon-regulated restriction factors O. Haller, F. Weber and G. Kochs; 14. Poxvirus immune evasion A. Alcami; 15. Evasion of host defence systems by African swine fever virus L. K. Dixon; 16. Murid herpesvirus 4 as a model for gammaherpesvirus pathogenesis J. P. Stewart, D. Hughes, L. Roaden and B. Ebrahimi; Index....