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Informationen zum Autor Dr Andrew Hadley is Division Manager at the International Blood Group Reference Laboratory, and Senior Scientist at the Bristol Institute for Transfusion Sciences, University of Bristol. Professor Peter Soothill is Professor of Maternal and Fetal Medicine in the Department of Obstetrics and Gynaecology, St Michael's Hospital and University of Bristol. Zusammenfassung The alloimmune disorders of pregnancy arise from maternal immunisation to fetal blood cells. The effective prevention! diagnosis and management of these disorders involves a team management approach. This is an authoritative overview suitable for trainees in obstetrics! materno-fetal medicine! transfusion medicine and clinical immunology. Inhaltsverzeichnis Preface Andrew G. Hadley and Peter Soothill; 1. Pathophysiology of the alloimmune cytopenias Andrew G. Hadley and Craig Turner; 2. Blood group antibodies in haemolytic disease of the fetus and newborn Geoff Daniels; 3. Basis and practice of screening for haemolytic disease of the fetus and newborn Geoff Poole; 4. Epidemiology and screening for alloimmune thrombocytopenia Lorna M. Williamson and Michael F. Murphy; 5. Principles of antibody-mediated immune suppression and the prevention of maternal Rh(D) alloimmunisation Belinda Kumpel; 6. The clinical application of anti-D prophylaxis Stan Urbaniak; 7. Fetal genotyping Neil D. Avent; 8. Laboratory assays to determine the severity of haemolytic disease of the fetus and newborn Andrew G Hadley; 9. Assessing the severity of haemolytic disease of the fetus and newborn: clinical aspects Sherif Abdel-Fattah and Peter Soothill; 10. Antenatal therapy for haemolytic disease of the fetus and newborn Kenneth J. Moise and Paul W. Whitecar; 11. Neonatal therapy for haemolytic disease of the newborn Glynn Russell and Nic Goulden; 12. The diagnosis of alloimmune thrombocytopenia Andrew Hadley; 13. The diagnosis of alloimmune neutropenia Geoff Lucas; 14. Fetal and neonatal treatment of alloimmune thrombocytopenia Michael Murphy, Rachel Rayment, David Allen and David Roberts; Index....
