The Complete Spleen - Structure, Function, and Clinical Disorders

Since the publication of The Complete Spleen: Structure, Function, and Clinical Disorders under the title of The Spleen in 1990, there has appeared a wealth of new information that now demands incorporation into the diagnosis and management of patients with splenic disorders. In this 2nd edition, an international panel of distinguished clinical and scientific investigators has thoroughly revised and updated Professor Anthony Bowdler's classic work, emphasizing those functions principally reserved to the spleen, especially the spleen's microvasculature, uniquely adapted to particle filtration, and the consequent mechanisms of its immune responses.
Among the disease aspects critically surveyed in rich detail are the causes of splenic enlargement, the meaning of hypersplenism, hyposplenism and its causes and management, and the unusual cytopenias that accompany the disorders of the spleen, including those caused by maldistribution and dilutional anemias. Diseases given focused attention include the myelo- and lymphoproliferative disorders, hemolytic diseases, and the sickle-cell disorders. These are followed by details of the radiological examination of the spleen, of the present status of surgical intervention, with emphasis on tissue and functional conservation, and of the recently developed laparoscopic methods.
Comprehensive and state-of-the-art, The Complete Spleen: Structure, Function, and Clinical Disorders makes available to all physicians and clinical researchers a coherent account of today's dramatically more detailed knowledge of the spleen and its unique functions as part of the immune system, as well as our optimal current strategies for the management of its pathologies.

List of contents

I. The Structure and Function of the Spleen.- 1 The Anatomy of the Spleen.- 2 The Microanatomy of the Mammalian Spleen: Mechanisms of Splenic Clearance.- 3 Splenic Microcirculatory Blood Flow and Function with Respect to Red Blood Cells.- 4 The Immune Functions of the Spleen.- 5 The Role of the Spleen in Hemostasis.- II. Characteristics of the Disordered Spleen.- 6 The Pathology of the Spleen.- 7 Splenic Pooling and Survival of Blood Cells.- 8 Dilutional Anemia: Abnormalities of Blood Volume in Disorders of the Spleen.- III. Clinical Aspects of Disorders of the Spleen.- 9 The Clinical Significance of the Spleen.- 10 Hyposplenism.- 11 The Relationship of the Spleen to Infection.- 12 Hemolysis and Thrombocytopenia.- 13 Myeloproliferative Disorders.- 14 The Spleen in Lymphoproliferative Disease.- 15 The Spleen in Sickle Cell Disease.- 16 Imaging of Spleen Disorders.- 17 Surgery of the Spleen.

Summary

In this thoroughly revised and updated second edition, a panel of distinguished clinical researchers from around the world takes stock of the wealth of new knowledge about the human spleen and applies it to the pathology and treatment of splenic diseases. This much enriched understanding encompasses the spleen's complex role in immunological defense, the recently defined function of particulate filtration by the spleen, and the structural basis for the functions of the spleen, most particularly the microvasculature around which it is organized. Among the diseases and disorders of the spleen considered in detail are splenomegaly, the consequences and management of hyper- and hyposplenism, and "dilutional anemia." Recent advances in splenic surgery are also reviewed, especially those techniques intended to preserve at least partial function while removing the greater part of the organ.

Additional text

"There are detailed descriptions of the immune functions of the spleen as well as excellent photographs of the pathology of different splenic diseases. In the clinical aspects of the disorders of the spleen, there is a well thought out sequence of discussions about the various disorders and their ! clinical consequences. There are detailed CT scan images demonstrating different splenic disorders and excellent illustrations of the different surgical techniques on the spleen. . .This is an outstanding compendium of diseases related to the spleen. It gives the reader a complete and well-written view of this organ and its disorders. It is a well illustrated and a well thought out book. It provides the clinician with clear plans for treatment of various disorders, including surgical procedures, and provides the physician with up-to-date methods to diagnose particular splenic disorders. I found the surgical section to be particularly clear and well written. I would highly recommend this book to anyone with an interest in this organ. Although the spleen is a typically a mysterious organ to most of us, after reading this book, one will have a much better concept about its structure and function. "-Doody's Health Sciences Book Review Journal

"...This is an authoritive and inspirational book and would appeal to pathologists, microbiologists, surgeons and interested students." - European Journal of Haematology

Report

"There are detailed descriptions of the immune functions of the spleen as well as excellent photographs of the pathology of different splenic diseases. In the clinical aspects of the disorders of the spleen, there is a well thought out sequence of discussions about the various disorders and their ! clinical consequences. There are detailed CT scan images demonstrating different splenic disorders and excellent illustrations of the different surgical techniques on the spleen. . .This is an outstanding compendium of diseases related to the spleen. It gives the reader a complete and well-written view of this organ and its disorders. It is a well illustrated and a well thought out book. It provides the clinician with clear plans for treatment of various disorders, including surgical procedures, and provides the physician with up-to-date methods to diagnose particular splenic disorders. I found the surgical section to be particularly clear and well written. I would highly recommend this book to anyone with an interest in this organ. Although the spleen is a typically a mysterious organ to most of us, after reading this book, one will have a much better concept about its structure and function. "-Doody's Health Sciences Book Review Journal

"...This is an authoritive and inspirational book and would appeal to pathologists, microbiologists, surgeons and interested students." - European Journal of Haematology

Product details

• Assisted by: Anthony J. Bowdler (Editor), Anthon J Bowdler (Editor), Anthony J Bowdler (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 25.10.2010
• EAN: 9781617370717
• ISBN: 978-1-61737-071-7
• No. of pages: 331
• Dimensions: 213 mm x 21 mm x 281 mm
• Weight: 868 g
• Illustrations: XVIII, 331 p. 146 illus.
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; C, Medicine, Gastroenterology, blood cell;cell;imaging;pathology;surgery