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Informationen zum Autor Valery A Petrenko, Professor in the Department of Pathobiology at Auburn University, graduated from Moscow State University, Russia and received his PhD and DSc degrees in chemistry from the Zelinski Institute of Organic Chemistry, Moscow and Moscow State University, and Honor Rank of Professor in Molecular Biology from the Supreme Attestation Committee of Russia. In 1993 he joined the faculty of University of Missouri-Columbia as Visiting Professor and Research Professor, and in 2000-the faculty of Auburn University as Professor. In Auburn, Dr Petrenko established a research program focused on the development of diagnostic and therapeutic probes using phage display technique. Dr Petrenko is recipient of grants from the Army Research Office and the National Institute of Health, recipient of the Pfizer Animal Health Award for Research Excellence and CoPI in several collaborative grants. He is a member of the American Chemical Society and his major scientific interests are - monitoring and detection of biological threats, targeted drug delivery and diagnosis of infectious diseases and cancer. Valery Petrenko pioneered multivalent phage display (landscape phage) in 1989 and has published many peer reviewed papers and book chapters on the applications of the phage techniques. He was a recipient of several grants from ARO, DARPA and NIH and currently has an approximate $2 million grant from the NIH aimed at phage-driven drug delivery. Klappentext Bacteriophages have recently emerged as a result of the evolution of phage display techniques. In opposite to other nanomaterials, the bacteriophages have a unique feature: their structure and function are encrypted in their genomic DNA, which can be intentionally modified or even rewritten using routine genetic engineering techniques. Recently, phage - as a new kind of nanomaterial has attracted attention of specialists working in the boundaries of the field and even further afield from genetics and molecular biology, such as pharmaceutical science, material science, microelectronics, biosensors, detection, environmental sciences, etc. This comprehensive book, of value to researchers in all fields, brings the phage display technique closer to specialists in areas of medicine, science and technology, where phage-derived nanomaterials can be most beneficial. Zusammenfassung This book brings the phage display technique closer to specialists in areas of medicine! science and technology! where phage-derived nanomaterials can be most beneficial. Inhaltsverzeichnis Structure of Filamentous Phage Particles and Their Components; Amplification and Self Assemblage of Phage Particles; Evolution of Phage Display towards Nanotechnology; Imaging with Phage Derived Probes; Phage-Derived Vectors for Gene Delivery; Phage-Mediated Drug Delivery; Phage Immunogens and Vaccines; Phage-Templated Synthesis of Inorganic Nanomaterials; Phage-based Biorecognition Interfaces in Biosensors; Reporting phage for detection of biological threats; Site-Directed Chemical Modification of Phage Particles; Combinatorial Phage Nanobiotechnology...
