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Informationen zum Autor Kendall Hoyt Klappentext Despite large-scale government demand for new vaccines in the past decade, few have materialized. Vaccine innovation has been falling since World War II. Hoyt's timely investigation asks why, and teaches lessons for our efforts to rebuild biodefense capabilities when the financial payback for a vaccine is low but the social returns are high. Zusammenfassung Despite large-scale government demand for new vaccines in the past decade, few have materialized. Vaccine innovation has been falling since World War II. Hoyt’s timely investigation asks why, and teaches lessons for our efforts to rebuild biodefense capabilities when the financial payback for a vaccine is low but the social returns are high.
List of contents
Contents Introduction 1. Disease, Security, and Vaccines 2. Historical Patterns of Vaccine Innovation 3. Vaccine Development during World War II 4. Wartime Legacies 5. The End of an Era 6. Biodefense in the Twenty-First Century 7. The Search for Sustainable Solutions Appendix 1 Vaccine License Data, 1903-1999 Appendix 2 Developmental History of Vaccines Licensed in the United States, 1903-1999 Appendix 3 Military Contributions to Licenses Representing Innovative Activity Notes Acknowledgments Index
Report
I've had the good fortune to know past leaders in vaccine development. I have also observed the present model from an orchestra seat since the mid-80s. The technology is now a given. Long Shot challenges us to find the leadership and the will to rediscover the way ahead for orphan medical countermeasures.
-- David R. Franz, former commander, United States Army Medical Research Institute of Infectious Diseases
At a time of continuing concern regarding bioterrorism and emerging diseases, the development of new vaccines is essential. Long Shot, an original, thoroughly documented and persuasive work utilizes extensive data from economics, science and organizational politics to demonstrate that the current failure of vaccine innovation presents a threat that U.S. policy makers ignore at their peril.
-- John Ellis van Courtland Moon, Professor of History, Emeritus, Fitchburg State College
Innovations in research and development and the importance of vaccines to public health--second only to clean water--are vital issues...All citizens need to know more about these subjects.
-- Mary Chitty Library Journal
The history of vaccine development records periods of pronounced and of minimum productivity. The latter, according to Hoyt, describes the current development status and represents a danger to both civilian and military needs, most particularly to national defense objectives...Considering the magnitude of the problems, Hoyt's suggestions are well presented and reasonable and reflect an acute awareness of overall issues and concerns.
-- R. S. Kowalczyk Choice
