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The Second World War gave rise to a previously inconceivable number of peripheral nerve injuries. Only later on did these injuries occasion renewed intensive research in this field of neurosurgery. Among the factors which have promoted this development is the operating microscope with more refined surgical techniques. Of course, surgery of peripheral nerve injuries in peacetime is not to be compared with that in wartime. Only rapid wound healing enables a secondary suture to be performed at a favorable time, after about four weeks. Besides in most cases the defect of substance is not as great as in war injuries, in which the so-called "critical resection length" (Seddon) was the cause of the greatest difficulties and consti tuted the crucial obstacle to good success. The experienced surgeons of the Second World War always knew that the specified dimensions were far too great for the critical resection length. They could only resort to attempting a suture even when there was a great gap be tween the ends of the nerves. Precise information was not available on direct damage to the axis cylinder or alteration due to vascular factors when stretching the various nerves, above all during the later mobilization of joint decompressions. In my opinion, the experimental investigations of the author can make a contribution here. The precisely executed and afterwards carefully analyzed experiments appear very likely to be applicable to human conditions as regards their percentages of total nerve length.
List of contents
A. Introduction.- B. The Problem.- C. Material and Methods.- I. Selection of Appropriate Subjects.- II. Anatomy of the Sciatic Nerve in Rabbits.- III. Operative Technique.- IV. Determination of the Critical Resection Length.- V. Identification of Physical Parameters.- VI. Clinical Studies.- VII. Histological Studies.- D. Results.- I. Mechanical Properties.- II. Clinical Observations.- III. Macroscopic Findings.- IV. Histological Results.- E. Synopsis of All Results and Their Clinical Relevance.- I.- II.- F. Summary.- References.
