Supplementary Mutagenicity Tests - Ukems Recommended Procedures

Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.

List of contents

Steering group; Contributors; List of abbreviations; 1. Introduction D. J. Kirkland; 2. Geonotoxicity studies using yeast cultures T. M. Brooks et al.; 3. In vivo rat liver UDS assay J. C. Kennelly et al.; 4. Measurement of covalent binding to DNA in vivo C. N. Martin et al.; 5. Mammalian germ cell cytogenics C. Tease et al.; 6. The rodent dominant lethal assay L. M. Holmstrom et al.; Index.

Summary

Originally published in 1993, this volume describes a complementary selection of tests to those described in the companion volume Basic Mutagenicity Tests (Cambridge University Press, 1990). These supplementary tests were used to assess risks of in vitro mutagenicity in those instances where the basic safety tests were inconclusive.

Product details

• Authors: David J. Fox Kirkland
• Assisted by: Margaret Fox (Editor), Fox Margaret (Editor), David J. Kirkland (Editor), Kirkland David J. (Editor)
• Publisher: Cambridge University Press ELT
• Languages: English
• Product format: Paperback / Softback
• Released: 09.06.2011
• EAN: 9780521116961
• ISBN: 978-0-521-11696-1
• No. of pages: 178
• Subjects: Natural sciences, medicine, IT, technology > Medicine > General; TECHNOLOGY & ENGINEERING / Environmental / Pollution Control, MEDICAL / Genetics, MEDICAL / Toxicology, Oncology, Pollution control, MEDICAL / Oncology / General