Excitatory Amino Acids - From Genes to Therapy

In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.

List of contents

Glutamate Receptor Channels, RNA Editing, and Epileps. Regulation of Glutamate Receptor Gene Expression in Global Ischemia.- Factors Regulating Excitotoxic Neurodegeneration.- Excitotoxicity, Genetics, and Neurodegeneration in Amyotrophic Lateral Sclerosis.- NO-NMDA Receptor Interactions.- AMPA Receptor GluR-B Subunit mRNA in Rats.- Quantitative Estimation of NMDA Receptor-Mediated Calcium Entry in Central Neurons.- Calcium Permeability of Glutamate-Gated Channels in the CNS.- Localisation and Surface Expression of the AMPA Receptor Subunit ...

Product details

• Publisher: Springer, Berlin
• Languages: English
• Product format: Hardback
• Released: 01.01.1998
• EAN: 9783540633877
• ISBN: 978-3-540-63387-7
• No. of pages: 208
• Weight: 428 g
• Illustrations: w. 45 figs.
• Series: Ernst Schering Research Foundation Workshop; Ernst Schering Research Foundation Workshop
• Subject: Natural sciences, medicine, IT, technology > Medicine > Pharmacy