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This volume of Current Topics in Microbiology and Immunology covers diverse topics related to intradermal immunization. The chapters highlight the effectiveness of intradermal immunization in experimental animal models or in clinical practice, all supporting the view that intradermal immunization is at least as good as other immunization routes. Keeping in mind that current vaccines are not specially designed for intradermal immunization, but show comparable efficiency even at reduced dosages, this underlines the great potential for the skin as a vaccination site. Hopefully, the overview in this volume will encourage vaccine designers to focus on this promising immunization route, and in addition, to inspire them to develop vaccines that are especially optimized for intradermal immunization.
List of contents
Preface.- Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies.- Insight into the immunobiology of human skin and cutaneous dendritic cell subsets to perfection intradermal vaccination design.- Delivery systems for intradermal vaccination.- Targeting skin dendritic cells to improve intradermal immunization.- Intradermal Rabies vaccination: the evolution and future of pre- and post-exposure prophylaxis.- Intradermal vaccination to protect against yellow fever and influenza.- The dermis as a portal for dendritic cell-targeted immunotherapy of cutaneous melanoma.- DNA vaccines and intradermal vaccination by DNA tattooing.- Subject index
Summary
This volume of Current Topics in Microbiology and Immunology covers diverse topics related to intradermal immunization. The chapters highlight the effectiveness of intradermal immunization in experimental animal models or in clinical practice, all supporting the view that intradermal immunization is at least as good as other immunization routes. Keeping in mind that current vaccines are not specially designed for intradermal immunization, but show comparable efficiency even at reduced dosages, this underlines the great potential for the skin as a vaccination site. Hopefully, the overview in this volume will encourage vaccine designers to focus on this promising immunization route, and in addition, to inspire them to develop vaccines that are especially optimized for intradermal immunization.
