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Informationen zum Autor Marc Vandevelde Dr.med.vet., DECVN is a professor of neurology in the Division of Neurological Sciences, Vetsuisse Faculty at the University of Bern, Switzerland. Robert J. Higgins BVSc, MS, PhD, DACVP is a professor of pathology in the Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, at the University of California Davis, Davis, California, USA. Anna Oevermann Dr. med.vet., DECVP is an associate professor of neuropathology in the Division of Neurological Sciences , Vetsuisse Faculty at the University of Bern, Switzerland. Klappentext Introducing the theoretical and practical basics of veterinary neuropathology, this concise and well illustrated book is an essential basic diagnostic guide for pathologists, neurologists and diagnostic imaging specialists. It presents readers with strategies to deal with neuropathological problems, showing how to interpret gross and histological lesions using a systematic approach based on pattern recognition.It starts with an overview of the general principles of neuroanatomy, neuropathological techniques, basic tissue reaction patterns, and recognition of major lesion patterns. The book goes on to cover vascular diseases, inflammatory diseases, trauma, congenital malformations, metabolic-toxic diseases, neoplasia and degenerative diseases mainly of the central nervous system. In the respective chapters pathologists can quickly find information to support their daily diagnostic workup for both small and large domestic species. Based on the authors' extensive diagnostic and post graduate teaching experience as well as the inclusion of MRI as it relates to neuropathology, this book also offers a comprehensive but basic analysis of veterinary neuropathology that neurologists and other MRI users will find very useful.* An essential manual for daily diagnostic work* Richly illustrated with high quality colour gross, histological and MRI images* Includes a section on the function and use of MRI (by Johann Lang, DECVDI)* Accompanied by a website presenting MRI sequences for interpretation and correlation with neuropathological findings edited by Johann Lang (University of Bern, Switzerland) and Eric Wiesner (University of California, Davis, USA): www.wiley.com/go/vandevelde/veterinaryneuropathology Zusammenfassung A concise, well-illustrated book which introduces the theoretical and practical basics of veterinary neuropathology, based on the authors' extensive clinical and teaching experience. The book teaches neuropathology from scratch not only for pathologists and neurologists but also other interested groups - particularly imaging specialists. Inhaltsverzeichnis Preface ix Foreword x 1 General neuropathology 1 1.1 Principles of neuroanatomy for diagnostic neuropathologists 1 1.1.1 Anatomical orientation by using the ventricular system 1 1.1.2 Major anatomical regions of interest 2 1.1.3 Histological neuroanatomy 7 1.2 Neuropathological techniques 11 1.2.1 Necropsy techniques 11 1.2.2 Brain sectioning, macroscopic inspection and sampling for histology 12 1.3 Basic tissue reaction patterns 14 1.3.1 Reactions of neurons to injury 14 1.3.2 Oligodendrocytes 20 1.3.3 Astrocytes 20 1.3.4 Microglia/macrophages 22 1.3.5 CSF spaces 23 1.3.6 Blood vessels 23 1.3.7 Disturbance of water balance: edema 24 1.3.8 Artifacts, postmortem degeneration, pseudolesions and old age 26 1.4 Recognizing major lesion patterns 28 1.4.1 The major lesion patterns 28 1.4.2 Lesion distribution pattern 31 1.4.3 Classification of neurological diseases 31 1.4.4 General strategy 33 1.5 Neuropathology in the clinics: magnetic resonance imaging (MRI) 33 1.5.1 Basic MRI physics 33 1.5.2 Principles of i...
