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The organizer area plays a central role in the formation of the embryonic axis and the central nervous system of all vertebrates including the human fetus. In The Vertebrate Organizer outstanding molecular development biologists and embryologists report their latest approaches in this fascinating research area using different vertebrate model organisms. The presented data are of central importance for the understanding of early human embryogenesis.
List of contents
Early Steps Leading to the Formation of the Organizer.- 1 Maternal VegT and ?-Catenin: Patterning the Xenopus Blastula.- 2 Short-Versus Long-Range Effects of Spemann's Organizer.- 3 Formation of the Endoderm in Xenopus.- 4 Role of Fox Genes During Xenopus Embryogenesis.- The Role of the Organizer.- 5 The Molecular Nature of Spemann's Organizer.- 6 The Community Effect in Xenopus Development.- 7 Regulation of Spemann's Organizer Formation.- 8 Transcriptional Repression in Spemann's Organizer and the Formation of Dorsal Mesoderm.- 9 Wnt Signals and Antagonists: The Molecular Nature of Spemann's Head Organizer.- 10 Basic Helix-Loop-Helix Proneural Genes and Neurogenesis in Xenopus Embryos.- 11 Organizer Activities Mediated by Retinoic Acid Signaling.- 12 Wnt Signalling and Regulation of Gastrulation Movements.- The Organizer and Pattern Formation.- 13 How Cell-Cell Adhesion Contributes to Early Embryonic Development.- 14 Patterning Non-neural Ectoderm by Organizer-Modulated Homeodomain Factors.- Axis Formation and Organogenesis.- 15 Embryonic Organogenesis and Body Formation in Amphibian Development.- 16 Organizing the Eye.- 17 A Critical Role for Retinoid Receptors in Axial Patterning and Neuronal Differentiation.- 18 Molecular Patterning of the Embryonic Brain.- 19 Epidermal, Neuronal and Glial Cell Fate Choice in the Embryo.- 20 Downstream of the Organizer: The Xenopus Cement Gland as a Model for Organ Positioning and Differentiation.- Organizer Formation in Different Vertebrates.- 21 The Organizer in Amphibians with Large Eggs: Problems and Perspectives.- 22 Formation and Functions of the Gastrula Organizer in Zebrafish.- 23 Hensen's Node: The Embryonic Organizer of the Chick.- 24 Formation and Function of the Mouse Organizer.
Summary
The organizer area plays a central role in the formation of the embryonic axis and the central nervous system of all vertebrates including the human fetus. In The Vertebrate Organizer, outstanding molecular development biologists and embryologists report their latest approaches in this fascinating research area using different vertebrate model organisms. The presented data is of central importance for the understanding of early human embryogenesis.
Additional text
From the reviews:
"Horst Grunz has done a great job in editing a splendid book on vertebrate early development … and has collected a great team of leading researchers as authors for the different chapters. … The book is nicely produced and most chapters well illustrated. … The book is also well bound and will withstand intense use in libraries, laboratories and offices. … it is a very fine book indeed, and can be recommended to research workers and advanced students of induction and pattern formation." (Lennart Olsson, Journal of Zoological Systematics and Evolutionary Research, Vol. 43 (3), 2005)
Report
From the reviews:
"Horst Grunz has done a great job in editing a splendid book on vertebrate early development ... and has collected a great team of leading researchers as authors for the different chapters. ... The book is nicely produced and most chapters well illustrated. ... The book is also well bound and will withstand intense use in libraries, laboratories and offices. ... it is a very fine book indeed, and can be recommended to research workers and advanced students of induction and pattern formation." (Lennart Olsson, Journal of Zoological Systematics and Evolutionary Research, Vol. 43 (3), 2005)
