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Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.
List of contents
1 Animal models of autoimmune thyroiditis: recent advances.- 2 Thyroid autoantigens.- 3 Autoimmune hypothyroidism.- 4 Graves' disease: progress to date and future prospects.- 5 Postpartum thyroiditis.- 6 Thyroid-associated ophthalmopathy.- 7 Beta cell antigens.- 8 Aetiology and pathogenesis of insulin-dependent diabetes mellitus (IDDM).- 9 Addison's disease and related polyendocrinopathies.- 10 Premature ovarian failure.- 11 Pituitary autoimmunity.- 12 Autoimmune gastritis and pernicious anaemia.- 13 Vitiligo.
Summary
Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.
