The Meaning of Nucleocytoplasmic Transport

The means by which proteins and RNAs are exchanged between cytoplasm and nucleus have interested cell biologists for many years, and the field has seen a number of exciting recent advances. Much has been learned about the intricate architecture of the nuclear pore-complex, the mechanisms by which transport substrates are sorted, and the supply of energy for exchange processes. This book attempts a general review of the growing body of knowledge. However, the authors challenge the presumptions implicit in some interpretations of the evidence, re-examining the concept of "transport" within cells, and suggesting that lessons learned from nucleocytoplasmic transport studies can elucidate wider aspects of cell biology.

List of contents

1. Perspectives in Transport.- 2. The Vagaries of Diffusion.- 3. Cellular Structures and Nucleocytoplasmic Transport.- 4. Events at the Pore-Complex.- 5. Events Involving the Nucleoskeleton and Cytoskeleton.- 6. Regulation and Pathologies of Nucleocytoplasmic Transport.- 7. Evaluation of a Model.

Product details

• Authors: Paul Agutter, Paul S Agutter, Paul S. Agutter, Philip L Taylor, Philip L. Taylor
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 14.11.2013
• EAN: 9783662225042
• ISBN: 978-3-662-22504-2
• No. of pages: 200
• Illustrations: VIII, 200 p. 5 illus.
• Series: Molecular Biology Intelligence Unit; Molecular Biology Intelligence Unit
• Subject: Natural sciences, medicine, IT, technology > Biology > General, dictionaries