Pore-Forming Toxins

Pore-forming toxins are virulence factors produced by a great variety of pathogenic bacteria ranging from the Gram-positive Staphylococcus aureus to the Gram-negative Helicobacter pylory. The recent studies reviewed in this volume describe the progress that has been made in dissecting the different steps of the mode of action of these proteins which generally include binding to specific cell surface receptors, oligomerization into ring like structures and membrane perforation.

List of contents

List of Contents.- Pore-Forming Bacterial Protein Toxins: An Overview.- The Cholesterol-Dependent Cytolysins.- Aerolysin from Aeromonas hydrophila and Related Toxins.- Staphylococcal Pore-Forming Toxins.- RTX Toxin Structure and Function: A Story of Numerous Anomalies and Few Analogies in Toxin Biology.- Helicobacter pylori Vacuolating Cytotoxin: Cell Intoxication and Anion-Specific Channel Activity.- Pore-Forming Colicins and Their Relatives.

Product details

• Assisted by: Gisou van der Goot (Editor), Giso van der Goot (Editor), Gisou van der Goot (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 13.11.2013
• EAN: 9783642625459
• ISBN: 978-3-642-62545-9
• No. of pages: 168
• Dimensions: 155 mm x 10 mm x 235 mm
• Weight: 283 g
• Illustrations: IX, 168 p.
• Series: Current Topics in Microbiology and Immunology; Current Topics in Microbiology and Immunology
• Subjects: Natural sciences, medicine, IT, technology > Biology > Microbiology; Protein, C, Biology, Helicobacter pylori, microbiology, Toxin, cell, proteins, membrane, Biomedical and Life Sciences, receptor, virulence, cytolysins, cell intoxication, pore-forming colicins