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Dr. Robert Volpé and his distinguished contributors comprehensively review the latest thinking about the theoretical, experimental, and clinical aspects of autoimmune endocrine disorders. These world-renowned experts examine the pathogenesis and immunogenetics of these diseases, discuss the role of sex hormones in autoimmunity, and elucidate the nature of autoantigens. They also provide clinical detail on a wide variety of autoimmune endocrinopathies, including autoimmune thyroid disease, Graves' ophthalmopathy and dermopathy, human insulin-dependent diabetes mellitus, and autoimmune adrenocortical failure. Postpartum autoimmune endocrine syndromes, autoimmune hypophysitis, and the polyglandular autoimmune syndromes are also discussed in detail. Comprehensive and authoritative, Autoimmune Endocrinopathies provides today's most up-to-date understanding of the etiology and pathogenesis of autoimmune endocrine diseases.
List of contents
1 Normal Mechanisms for Self-Tolerance.- 2 Immunoregulation in Experimental Autoimmune Endocrine Disease.- 3 The Genetic Susceptibility to Type 1 (Insulin-Dependent) Diabetes Mellitus and the Autoimmune Thyroid Diseases: From Epidemiological Observations to Gene Mapping.- 4 Experimental Models for Autoimmune Thyroid Disease: Recent Developments.- 5 Animal Models for Insulin-Dependent Diabetes Mellitus.- 6 The Epidemiology of Autoimmune Thyroid Disease.- 7 Sex Hormones and Immune Responses.- 8 Autoantigens in the Autoimmune Endocrinopathies.- 9 The Immunology of Human Autoimmune Thyroid Disease.- 10 Thyroid-Associated Ophthalmopathy and Dermopathy.- 11 Postpartum Autoimmune Endocrine Syndromes.- 12 Etiology and Pathogenesis of Human Insulin-Dependent Diabetes Mellitus.- 13 Autoimmune Adrenocortical Failure.- 14 Autoimmune Hypophysitis.- 15 The Polyglandular Autoimmune Syndromes.- 16 Autoimmune Endocrinopathies in Female Reproductive Dysfunction.- 17 Immunotherapy and Prevention of Autoimmune Endocrinopathies.
Report
This book would serve as an excellent reference for researchers, students, and fellows, as well as clinicians who desire a deeper appreciation for the pathogenesis of many of the diseases in the patients they treat. . .an extremely useful and interesting source."Doody's Health Science Book Review Journal
"The authors of this text are some of the world leaders in the field. . .this book provides an excellent overview of current knowledge on the subject of autoimmune endocrine diseases,, and as such is of great interest to the endocrinologist with an interest in immunology, and indeed to the immunologist with an interest in endocrinology. I recommend it highly."-The Endocrinologist
"The book is well referenced and contains many helpful tables and figures. It is of interest to all endocrinologists, immunologists, and diabetologists."-Journal of Pediatric Endocrinology & Metabolism
