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"Preface For much of the past century, projection radiography has been the workhorse in the diagnostic imaging clinic. Tomosynthesis, which introduces depth information to the x-ray radiographic image with little or no increase in radiation dose, could potentially replace projection radiography as we move into the twenty-first century. This book, Tomosynthesis Imaging, offers the most comprehensive resource to date for this new emerging imaging technology. Digital tomosynthesis imaging is a novel quasi-three dimensional x-ray imaging modality that has been primarily developed during the past two decades, owing to the availability of large-area digital x-ray detectors. The tomosynthesis image is reconstructed from a sequence of projection images that are acquired from a limited angle x-ray scan, therefore, conceptually, tomosynthesis might be considered as limited-angle CT. Because of the limited angle acquisition, resolution in the reconstructed volume is not isotropic. The resolution in image planes parallel to the detector surface is similar to the native detector resolution, but the resolution perpendicular to the detector surface direction is substantially worse, and depends on the scan arc length and on the size of the detail being imaged. Tomosynthesis imaging is being actively investigated for use in a variety of clinical tasks. Currently, tomosynthesis breast imaging is at the forefront, having received approval for clinical use in Europe and Canada in 2008, and FDA approval in the United States in 2011. Although conventional mammography has been very successful in reducing the breast cancer mortality rate, its sensitivity and specificity are less then desirable, especially for women with dense breast tissue"--Provided by publisher.
List of contents
Section I Introduction. The history of tomosynthesis. Section II System Design. System design and acquisition parameters for breast tomosynthesis. Detectors for tomosynthesis. Patient dose. Tomosynthesis with circular orbits. Tomosynthesis system modeling. Section III Image Reconstruction. Filtered back projection-based methods for tomosynthesis image reconstruction. Iterative image reconstruction design for digital breast tomosynthesis. Section IV System Performance. Fourier-domain methods for optimization of tomosynthesis (NEQ). Spatial-domain model observers for optimizing tomosynthesis. Observer experiments with tomosynthesis. section V Clinical Applications. Clinical applications of breast tomosynthesis. Chest tomosynthesis. Tomosynthesis applications in radiation oncology. Future developments in breast tomosynthesis. Index.
About the author
Ingrid Reiser, PhD, is a research associate (assistant professor) in the Department of Radiology at the University of Chicago. After receiving her PhD in physics from Kansas State University in 2002, she transitioned into medical physics research where she witnessed the presentation of the first breast tomosynthesis images at RSNA 2002 (Radiological Society of North America). Tomosynthesis captivated her interest and she has since investigated many aspects of tomosynthesis imaging, such as computer-aided detection, system modeling, and objective assessment. Her research interests further include image perception and observer performance, as well as tomosynthesis and CT image reconstruction.
Stephen J. Glick
, PhD, is a professor of radiology at the University of Massachusetts University Medical School and the director of the Tomographic Breast Imaging Research Laboratory. He earned his PhD from Worcester Polytechnic Institute (WPI) in 1991. Dr. Glick is the author of over 60 journal articles and 100 conference proceedings papers and 8 book chapters. Over the past decade, his research has been focused on 3D breast imaging techniques including digital breast tomosynthesis and breast CT with an emphasis on radiation dose, imaging technique optimization, advanced iterative reconstruction methods, detection studies for lesions and microcalcifications, and photon counting detector CT.
