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Informationen zum Autor Subhas C. Kundu, PhD, is a Research Coordinator and former European Research Area Chair and Professor at the 3B´s Research Group, I3Bs – Institute on Biomaterials, Biodegradables and Biomimetics of the University of Minho, Portugal. His research interests include silk biomaterial matrices for biomedical applications, including 3D in vitro cancer models for investigating tumour growth and progression. In addition, he is using natural-based biomaterials for 3D cancer modelling and drug screening. Klappentext Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area. Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering. Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering. Zusammenfassung The unique mechanical and chemical properties of this material and the ability to genetically tailor the protein has meant that this material is now being used increasingly for biomaterials and tissue engineering applications. This book discusses the properties and applications of silk for medical purposes. Inhaltsverzeichnis Contributor contact details Woodhead Publishing Series in Biomaterials Foreword Part I: Fundamentals, processing and types of silk biomaterials Chapter 1: Introduction to silk biomaterials Abstract: 1.1 Introduction 1.2 General information about silkworms 1.3 Silk proteins 1.4 Genetics of silkworms 1.5 Diseases of silkworms 1.6 Applications of silks 1.7 Application of silk protein fibroins 1.8 Application of silk protein sericins 1.9 Conclusion 1.10 Acknowledgments Chapter 2: Applications of silk biomaterials in tissue engineering and regenerative medicine Abstract: 2.1 Introduction 2.2 Silk scaffolds in tissue engineering and regenerative medicine 2.3 Hard tissue engineering 2.4 Soft tissue engineering 2.5 Tissue engineering for application in specific organs 2.6 Conclusion and future trends 2.7 Acknowledgments Chapter 3: Processing of Bombyx mori silk for biomedical applications Abstract: 3.1 Introduction 3.2 Modulation of silk biomaterial properties 3.3 Silk fibroin materials and their use in biomedical applications 3.4 Conclusion and future trends Chapter 4: Silk nanostructures based on natural and engineered self-assembly Abstract: 4.1 Introduction 4.2 Mechanisms of self-assembly in natural and engineered systems 4.3 Assembly of natural and recombinant silk proteins 4.4 Engineering the self-assembly of silk 4.5 Silk nano-architectures and their applications 4.6 Self-assembly in conjugation with other (bio)materials 4.7 Conjugation with natural and synthetic materials 4.8 Conclusion and future trends Chapter 5: Electrospun silk sericin nanofibers for biomedical applications Abstract: 5.1 Introduction 5.2 Application of silk sericin in the biomedical field 5.3 Electrospinning 5.4 Silk sericin nanofibers from electrospinn...
