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Informationen zum Autor RATHNAM CHAGUTURU, PHD, is the Founder & CEO of iDDPartners, a nonprofit think-tank focused on pharmaceutical innovation. He has more than thirty years of experience in executing new lead discovery projects and forging discovery partnerships. He is the Founding President of the International Chemical Biology Society and Editor-in-Chief of Combinatorial Chemistry and High Throughput Screening . He serves on several other editorial and scientific advisory boards along with NIH Study Sections, is the recipient of several awards, and is a much sought-after speaker at major national and international conferences, passionately advocating the virtues of collaborative partnerships in addressing the pharmaceutical innovation crisis. Klappentext Can academia save the pharmaceutical industry?The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr. Rathnam Chaguturu presents a case for collaboration between the pharmaceutical industry and academia that could reverse the industry's decline. Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships provides insight into the potential synergy of basing R&D in academia while leaving drug companies to turn hits into marketable products. As Founder and CEO of iDDPartners, focused on pharmaceutical innovation, Founding president of the International Chemical Biology Society, and Senior Director-Discovery Sciences, SRI International, Dr. Chaguturu has assembled a panel of experts from around the world to weigh in on issues that affect the two driving forces in medical advancement.* Gain global perspectives on the benefits and potential issues surrounding collaborative innovation* Discover how industries can come together to prevent another "Pharma Cliff"* Learn how nonprofits are becoming the driving force behind innovation* Read case studies of specific academia-pharma partnerships for real-life examples of successful collaboration* Explore government initiatives that help foster cooperation between industry and academiaDr. Chaguturu's thirty-five years of experience in academia and industry, managing new lead discovery projects and forging collaborative partnerships with academia, disease foundations, nonprofits, and government agencies lend him an informative perspective into the issues facing pharmaceutical progress. In Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships, he and his expert team provide insight into the various nuances of the debate. Zusammenfassung Reflecting the changing drug discovery landscape, Collaborative Drug Discovery offers an alternative model for the pharma industry. Here, readers discover how to pursue new avenues of drug discovery with academic partners focused on discovery research and industry on later-stage development. Inhaltsverzeichnis Foreword xv by Ferid Murad Preface xix About the Book xxv About the Editor xxvii Contributors xxix PART I: PERSPECTIVES ON COLLABORATIVE INNOVATION 1 If I have seen further it is by standing on the shoulders of giants. -Isaac Newton 1 PRODUCTIVE RELATIONSHIPS IN RESEARCH AND DEVELOPMENT BETWEEN GOVERNMENT, INDUSTRY, AND UNIVERSITIES 3 Wyatt R. Hume 2 DIVIDED WE FALL 11 William B. Mattes 3 INNOVATION: OPEN SOURCE AND NONPROFIT MODELS IN DRUG DISCOVERY 21 James M. Shaeffer and Sarah MacDonald 4 THE CHANGING FACE OF INNOVATION IN DRUG DISCOVERY 31 Litao Zhang and Carl Decicco 5 CURRENT TRENDS IN COLLABORATIVE DRUG DISCOVERY AND STRATEGIES TO DE-RISK PRECOMPETITIVE INITIATIVES 57 Anuradha Roy and Rathnam Cha...
