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Literally thousands of papers have been published on nitric oxide overthe past ten years. But there is no single monograph available that haspreviously attempted to summarize the important features of the roles ofnitric oxide in inflammation. The voluminous literature regarding theincredible range of chemical and biological effects of nitric oxide andreactive nitrogen oxide species, RNOS, may present a tangle of confusinginformation to the researcher. This volume brings together experts fromnitric oxide and inflammation research and presents a concise up-to-dateoverview as well as future aspects of this rapidly growing field.
List of contents
Regulation of the inducible nitric oxide synthase (iNOS) gene.- Superoxide anion release from inducible nitric oxide synthase.- Direct and indirect modulation of the inducible nitric oxide synthase by nitric oxide: feedback mechanisms in inflammation.- Nitric oxide regulation of eicosanoid production.- Local and systemic inflammation: role of poly (ADP-ribose) synthetase activation by reactive nitrogen species.- Nitric oxide regulation of leukocyte adhesion molecule expression.- Nitric oxide and leukocyte recruitment.- Nitric oxide regulation of lymphocyte function.- Role of nitric oxide and reactive oxygen species in arthritis.- Role of nitric oxide in chronic gut inflammation.- Nitric oxide and inflammatory disorders of the skin.- Roles of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury and ischemic preconditioning.- Nitric oxide and myocarditis.- Nitric oxide in shock: sepsis and hemorrhage.- Nitric oxide as a mediator of interleukin-2 induced cardiovascular toxicity and antitumor activity.
Summary
Literally thousands of papers have been published on nitric oxide over
the past ten years. But there is no single monograph available that has
previously attempted to summarize the important features of the roles of
nitric oxide in inflammation. The voluminous literature regarding the
incredible range of chemical and biological effects of nitric oxide and
reactive nitrogen oxide species, RNOS, may present a tangle of confusing
information to the researcher. This volume brings together experts from
nitric oxide and inflammation research and presents a concise up-to-date
overview as well as future aspects of this rapidly growing field.
