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This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is
placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment.
Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and their students or trainees.
List of contents
Contributors; Part I Introduction to Basic Neuroscience; Section Editor: Eric J. Nestler; Introduction: Eric J. Nestler; 1. Overview of brain development; John L.R. Rubenstein and Stewart A. Anderson; 2. Neurochemical systems in the central nervous system; Ariel Y. Deutch and Robert H. Roth; 3. Using basic electrophysiology to understand the neurobiology of mental illness; of Mental Illness; Evelyn K. Lambe and George K. Aghajanian; 4. Principles of signal transduction; Jean-Antoine Girault and Paul Greengard; 5. Mechanisms of neural plasticity; Eric J. Nestler and Steven E. Hyman; 6. Principles of molecular biology; Steven E. Hyman and Eric J. Nestler; 7. Functional genomics and models of mental illness; Lisa M. Monteggia, William A. Carlezon Jr, and Ralph J. DiLeone; 8. Epigenetics of psychiatric diseases; Bryan E. McGill and Huda Y. Zoghbi; Part II Methods of Clinical Neurobiological Research; S
About the author
Dennis Charney, Departments of Psychiatry, Neuroscience, & Pharmacology and Systems Therapeutics Mount Sinai School of Medicine, New York, NY.;Eric Nestler, Departments of Neuroscience, Psychiatry, and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY.
