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Informationen zum Autor Michael Wolfe , M.D is a former Chair of the FDA's advisory board for gastrointestinal drugs. He has achieved significant recognition for his interest in acid-related disorders, specifically GERD, NSAID-associated gastroduodenal ulcers, gastrinoma and other neuroendocrine tumors. He is on the editorial boards of Digestive Diseases and Sciences and Regulatory Peptides , and served as a member of the editorial board of The American Journal of Physiology. He has edited several textbooks, including Therapy of Digestive Disorders and Heartburn: Extinguishing the Fire Inside . In total, he's authored over 300 articles, chapters, abstracts and reviews. Robert C. Lowe , M.D. is the author of numerous book chapters and articles, and is co-editor of Educational Review Manual in Gastroenterology and GI Emergencies: A Quick Reference Guide. For the past 4 years, he has served as the chairman of the Medical Advisory Committee of the American Liver Foundation, New England Chapter and he is currently serving as a member of the Education and Training Committee of the American Gastroenterological Association. Klappentext Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the world's leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: Introduction of drug class Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations Dosing information for each GI condition and on- and off-label use Consistent use of both generic and trade names throughout Specific reference to drug use in pediatric patients and during pregnancy Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists. Zusammenfassung Provides a rapid-reference! expert guide to all you need to know about gastrointestinal drugs! including dosing! indications and pharmacology! and all brought to you by one of the world s leading names in GI drug development. No other book in this area can match this. Inhaltsverzeichnis List of contributors, xi Preface, xvi PART I: UPPER GI TRACT 1 Prokinetic agents and antiemetics, 3 Hemangi Kale and Ronnie Fass Prokinetics, 3 Antiemetic agents, 7 Recommended reading, 14 2 Proton pump inhibitors, 15 Wanda P. Blanton and M. Michael Wolfe Introduction, 15 Mechanism of action, pharmacodynamics, kinetics, 15 Clinical use and dosing, 18 Adverse effects/safety, 27 Recommended reading, 28 3 Histamine H2-receptor antagonists, 31 Kentaro Sugano Introduction, 31 Mechanism of action, 31 Pharmacology, 33 Clinical effectiveness, 40 Adverse events, 41 Recommended reading, 42 4 Prostaglandins and other mucosal protecting agents, 44 Carlos Sostres and Angel Lanas Introduction of drug class, 44 ...
