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In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including diffusion MRI, CT and MRI perfusion imaging, dual-energy CT, spectroscopy, imaging of hypoxia, and PET and other nuclear medicine studies. Applications of these techniques in a wide range of tumor types are explained in detail. The most appropriate ways to acquire and manage functional imaging data for common malignancies are reviewed, and due attention is paid to the analysis of information obtained with imaging biomarkers using a multiparametric approach. Numerous high-quality illustrations help to highlight the major teaching points.
List of contents
Clinical and therapeutic approach to functional oncological imaging: Cancer biology: What's important for imaging.- Imaging biomarkers in oncology as surrogate endpoints in clinical trials.- Role of functional-molecular imaging in oncology.- Radiotherapy and imaging.- New therapies and functional-molecular imaging.- Bioinformatics for cancer imaging. Imaging of cancer hallmarks: Imaging of angiogenesis.- Imaging of tumor metabolism: MR spectroscopy.- Imaging of tumor metabolism: 18-FDG PET.- Imaging of tumor metabolism: PET with other metabolites.- Imaging of hypoxia on PET.- Imaging of hypoxia on MRI. Functional imaging techniques in clinical use: Functional imaging in assessing and monitoring of treatment response.- Diffusion-weighted MR imaging.- Perfusion CT.- Perfusion MRI.- DCE-US: Evaluation of angiogenesis.- Spectroscopy in cancer.- Hybrid imaging: PET-CT and PET-MRI.- Dual and spectral energy CT: oncological applications.- US elastography: applications in tumors. Molecular imaging techniques in clinical use and in research: New molecular and functional imaging techniques.- Multiparametric imaging.
Report
"Text is written very clearly and is furthermore complemented by numerous high-quality illustrations that highlight key features. ... a useful manual to be used by a wide range and variety of students and professionals involved in the management of oncologic patients, including radiologists, nuclear physicians, oncologists, radiotherapists, oncologic surgeons, together with all the other professionals, also qualified in nonmedical disciplines, that may be interested in learning about advanced imaging techniques useful in oncology and more in general in modern medicine." (Christian Marsiglia and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 42, 2015)
