Forensics and Clinical Applications of Solid Phase Extraction, - Second Editio

Solid Phase Extraction (SPE) has become a powerful technique in the clean-up and concentration of samples in a wide variety of analytical techniques. This volume explains the principles behind SPE and provides protocols to help readers master extraction problems. These detailed methods are particularly suited to solving problems in forensic, pharmaceutical, and clinical chemistry. The book includes readily understandable explanations of the principals of pH, ion exchange, and co-polymeric mechanism-enhanced SPE. Each protocol is described in detail and contains an introduction outlining the principle behind the technique, a list of equipment and reagents, and troubleshooting advice.

List of contents

Introduction to Solid Phase Extraction. Silica-Based Solid Phase Extraction. The Chemistry of Bonded Phases. Bonded Phase Sorbent Synthesis. Solid Phase Extraction Equipment. Strategies for the Use of Solid Phase Extraction. Optimization of Solid Phase Extraction Methods. Separation of Analytes from their Matrices. Solid Phase Extraction Troubleshooting. Drug Methods for the Toxicology Laboratory. Selected Solid Phase Extraction for Drug Analysis. Chemical Derivatization. Appendices.

Summary

Solid Phase Extraction (SPE) has become a powerful and extensively used technique in the clean-up and concentration of samples in a wide variety of analytical techniques. This volume explains the principles behind SPE and provides protocols to help readers master extraction problems. These detailed methods are particularly suited to solving extraction problems in forensic, pharmaceutical, and clinical chemistry and include readily understandable explanations of the principals of pH, ion exchange, and co-polymeric mechanism-enhanced SPE. Each protocol is described in step-by-step detail and contains an introduction outlining the principle behind the technique, a list of equipment and reagents, troubleshooting advice, and tips on how to avoid known pitfalls.

Product details

• Authors: Thomas F August, Thomas F Telepchak August, Thomas F. August, Thomas F. (United Chemical Technologies August, Thomas F./ Telepchak August, Jeffery Hackett, Jeffery (United Chemical Technologies Hackett, Jeffery (United Chemical Technologies Bristol Pennsylvania USA) Hackett, Michael J (United Chemical Technologies Bristol Pennsylvania USA) Telepchak, Michael J. Telepchak, Michael J. (United Chemical Technologies Telepchak
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Hardback
• Release: 31.12.2023, delayed
• EAN: 9781466510951
• ISBN: 978-1-4665-1095-1
• No. of pages: 420
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Theoretical chemistry; Social sciences, law, business > Law > International law, foreign law; Analytische Chemie, LAW / Forensic Science, Science, SCIENCE / Chemistry / Analytic